Evidence map›Paper›PMID 34458179›Full record

ArticleAutopsy & case reports2021

Amniotic fluid embolism: lessons for rapid recognition and intervention.

Larry Nichols, Rema Elmostafa, Angela Nguyen, Keisha R Callins

Open access · diamondAbstract read
In one paragraph

Article in Autopsy & case reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.3field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 7 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Larry NicholsMercer University School of Medicine, Department of Pathology and Clinical Science Education, Macon, GA, USA.ORCID 0000-0002-0594-3273
Rema ElmostafaMercer University School of Medicine, Department of Pathology and Clinical Science Education, Macon, GA, USA.ORCID 0000-0001-5129-2339
Angela NguyenMercer University School of Medicine, Department of Pathology and Clinical Science Education, Macon, GA, USA.ORCID 0000-0002-5789-205X
Keisha R CallinsMercer University School of Medicine, Department of Pathology and Clinical Science Education, Macon, GA, USA.ORCID 0000-0002-6136-7768
Mercer University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Amniotic fluid embolism is a rare, often fatal complication of labor and delivery. The classic presentation is the sudden onset of a triad of clinical manifestations: hypoxia, hypotension and coagulopathy. Understanding of the syndrome as an immunologically mediated, complicated and often catastrophic maternal response to fetal or placental antigens is coming into focus. New treatments such as extracorporeal membrane oxygenation (ECMO) and better use of old treatments such as transfusion offer hope, but the condition is often rapidly fatal, so saving the maternal and fetal lives depends on rapid recognition of the syndrome. This series of three cases illustrates the clinical features enabling the rapid recognition needed for successful treatment of amniotic fluid embolism syndrome.

Indexed as

Amniotic fluid embolismAutopsyExtracorporeal membrane oxygenationMaternal mortality

Identifiers

PMID34458179
PMCPMC8387066
OpenAlexW3195588116

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.