Evidence map›Paper›PMID 34457426›Full record

ArticleBiomedical optics express2021

Optical coherence microangiography of the mouse kidney for diagnosis of circulatory disorders.

Arkady S Abdurashitov, Ekaterina S Prikhozhdenko, Oksana A Mayorova, Valentina O Plastun, Olga I Gusliakova, Natalia A Shushunova, Oleg A Kulikov, Valery V Tuchin, Gleb B Sukhorukov, Olga A Sindeeva

Open access · goldAbstract read
In one paragraph

Article in Biomedical optics express, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.7field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Heliyon · 2023
    Article
  5. Article
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 3 countries.

Arkady S AbdurashitovSkolkovo Institute of Science and Technology, Skolkovo Innovation Center, 3 Nobel str., Moscow 143005, Russia.ORCID https://orcid.org/0000-0003-0731-8364
Ekaterina S PrikhozhdenkoScience Medical Center, Saratov State University, 83 Astrakhanskaya str., Saratov 410012, Russia.ORCID https://orcid.org/0000-0003-2700-168X
Oksana A MayorovaScience Medical Center, Saratov State University, 83 Astrakhanskaya str., Saratov 410012, Russia.ORCID https://orcid.org/0000-0002-6440-3947
Valentina O PlastunScience Medical Center, Saratov State University, 83 Astrakhanskaya str., Saratov 410012, Russia.
Olga I GusliakovaScience Medical Center, Saratov State University, 83 Astrakhanskaya str., Saratov 410012, Russia.
Natalia A ShushunovaScience Medical Center, Saratov State University, 83 Astrakhanskaya str., Saratov 410012, Russia.
Oleg A KulikovOgarev Mordovia State University, 68 Bolshevistskaya str., Saransk 430005, Russia.
Valery V TuchinScience Medical Center, Saratov State University, 83 Astrakhanskaya str., Saratov 410012, Russia.ORCID https://orcid.org/0000-0001-7479-2694
Gleb B SukhorukovSkolkovo Institute of Science and Technology, Skolkovo Innovation Center, 3 Nobel str., Moscow 143005, Russia.
Olga A SindeevaSkolkovo Institute of Science and Technology, Skolkovo Innovation Center, 3 Nobel str., Moscow 143005, Russia.ORCID https://orcid.org/0000-0002-5288-4157
Saratov State University · RUNational Research Mordovia State University · RUQueen Mary University of London · GBSkolkovo Foundation · RU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Optical coherence tomography (OCT) has become widespread in clinical applications in which precise three-dimensional functional imaging of living organs is required. Nevertheless, the kidney is inaccessible for the high resolution OCT imaging due to a high light attenuation coefficient of skin and soft tissues that significantly limits the penetration depth of the probing laser beam. Here, we introduce a surgical protocol and fixation scheme that enables functional visualization of kidney's peritubular capillaries via OCT microangiography. The model of reversible/irreversible glomerulus embolization using drug microcarriers confirms the ability of OCT to detect circulatory disorders. This approach can be used for choosing optimal carriers, their dosages and diagnosis of other blood flow pathologies.

Identifiers

PMID34457426
PMCPMC8367229
OpenAlexW3175133233

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.