Evidence map›Paper›PMID 34457422›Full record

ArticleBiomedical optics express2021

Self-contained and modular structured illumination microscope.

Robin Van den Eynde, Wim Vandenberg, Siewert Hugelier, Arno Bouwens, Johan Hofkens, Marcel Müller, Peter Dedecker

Abstract read
In one paragraph

Article in Biomedical optics express, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Robin Van den EyndeLab for Nanobiology, Department of Chemistry, KU Leuven, Belgium.ORCID https://orcid.org/0000-0001-6548-3312
Wim VandenbergLab for Nanobiology, Department of Chemistry, KU Leuven, Belgium.ORCID https://orcid.org/0000-0002-5888-9100
Siewert HugelierLab for Nanobiology, Department of Chemistry, KU Leuven, Belgium.
Arno BouwensMolecular Imaging and Photonics, Department of Chemistry, KU Leuven, Belgium.
Johan HofkensMolecular Imaging and Photonics, Department of Chemistry, KU Leuven, Belgium.
Marcel MüllerLab for Nanobiology, Department of Chemistry, KU Leuven, Belgium.ORCID https://orcid.org/0000-0002-2264-3643
Peter DedeckerLab for Nanobiology, Department of Chemistry, KU Leuven, Belgium.ORCID https://orcid.org/0000-0002-1882-2075

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We present a modular implementation of structured illumination microscopy (SIM) that is fast, largely self-contained and that can be added onto existing fluorescence microscopes. Our strategy, which we call HIT-SIM, can theoretically deliver well over 50 super-resolved images per second and is readily compatible with existing acquisition software packages. We provide a full technical package consisting of schematics, a list of components and an alignment scheme that provides detailed specifications and assembly instructions. We illustrate the performance of the instrument by imaging optically large samples containing sequence-specifically stained DNA fragments.

Identifiers

PMID34457422
PMCPMC8367227

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.