Evidence map›Paper›PMID 34457394›Full record

ArticleBiomedical optics express2021

Minimizing OCT quantification error via a surface-tracking imaging probe.

Hyeon-Cheol Park, Ang Li, Honghua Guan, Chetan Bettegowda, Kaisorn Chaichana, Alfredo Quiñones-Hinojosa, Xingde Li

Abstract read
In one paragraph

Article in Biomedical optics express, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Hyeon-Cheol ParkDepartment of Biomedical Engineering, Johns Hopkins University, Baltimore, MD 21215, USA.ORCID https://orcid.org/0000-0002-0634-159X
Ang LiDepartment of Biomedical Engineering, Johns Hopkins University, Baltimore, MD 21215, USA.ORCID https://orcid.org/0000-0001-7461-9437
Honghua GuanDepartment of Electrical and Computer Engineering, Johns Hopkins University, Baltimore, MD 21218, USA.
Chetan BettegowdaDepartment of Neurosurgery, Johns Hopkins School of Medicine, Baltimore, MD 21287, USA.
Kaisorn ChaichanaDepartment of Neurologic Surgery, Mayo Clinic, Jacksonville, FL 32224, USA.
Alfredo Quiñones-HinojosaDepartment of Neurologic Surgery, Mayo Clinic, Jacksonville, FL 32224, USA.
Xingde LiDepartment of Biomedical Engineering, Johns Hopkins University, Baltimore, MD 21215, USA.

Funding

Intra-Operative, Label-Free Detection of Brain Cancer Infiltration with Quantitative Optical ImagingR01CA200399 · NCI · JOHNS HOPKINS UNIVERSITY · PI LI, XINGDE, QUINONES-HINOJOSA, ALFREDO · 2016 to 2020
$3.0M
NCI NIH HHS R01 CA200399
6 · The paper itself

Abstract

OCT-based quantitative tissue optical properties imaging is a promising technique for intraoperative brain cancer assessment. The attenuation coefficient analysis relies on the depth-dependent OCT intensity profile, thus sensitive to tissue surface positions relative to the imaging beam focus. However, it is almost impossible to maintain a steady tissue surface during intraoperative imaging due to the patient's arterial pulsation and breathing, the operator's motion, and the complex tissue surface geometry of the surgical cavity. In this work, we developed an intraoperative OCT imaging probe with a surface-tracking function to minimize the quantification errors in optical attenuation due to the tissue surface position variations. A compact OCT imaging probe was designed and engineered to have a long working distance of ∼ 41 mm and a large field of view of 4 × 4 mm

Identifiers

PMID34457394
PMCPMC8367274

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.