Evidence map›Paper›PMID 34457383›Full record

ArticleBiomedical optics express2021

Automatic threshold selection algorithm to distinguish a tissue chromophore from the background in photoacoustic imaging.

Azin Khodaverdi, Tobias Erlöv, Jenny Hult, Nina Reistad, Agnes Pekar-Lukacs, John Albinsson, Aboma Merdasa, Rafi Sheikh, Malin Malmsjö, Magnus Cinthio

Abstract read
In one paragraph

Article in Biomedical optics express, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Azin KhodaverdiDepartment of Biomedical Engineering, Faculty of Engineering, Lund University, SE-221 00 Lund, Sweden.
Tobias ErlövDepartment of Biomedical Engineering, Faculty of Engineering, Lund University, SE-221 00 Lund, Sweden.
Jenny HultDepartment of Clinical Sciences Lund, Skane University Hospital, Lund University, SE-221 00 Lund, Sweden.ORCID https://orcid.org/0000-0002-1503-1139
Nina ReistadDepartment of Physics, Faculty of Engineering, Lund University, SE-221 00 Lund, Sweden.ORCID https://orcid.org/0000-0002-7025-5725
Agnes Pekar-LukacsDepartment of Oncology and Pathology, Skane University Hospital, Lund University, SE-221 00 Lund, Sweden.
John AlbinssonDepartment of Clinical Sciences Lund, Skane University Hospital, Lund University, SE-221 00 Lund, Sweden.ORCID https://orcid.org/0000-0003-3106-937X
Aboma MerdasaDepartment of Clinical Sciences Lund, Skane University Hospital, Lund University, SE-221 00 Lund, Sweden.ORCID https://orcid.org/0000-0002-6298-5672
Rafi SheikhDepartment of Clinical Sciences Lund, Skane University Hospital, Lund University, SE-221 00 Lund, Sweden.ORCID https://orcid.org/0000-0002-8289-9114
Malin MalmsjöDepartment of Clinical Sciences Lund, Skane University Hospital, Lund University, SE-221 00 Lund, Sweden.
Magnus CinthioDepartment of Biomedical Engineering, Faculty of Engineering, Lund University, SE-221 00 Lund, Sweden.ORCID https://orcid.org/0000-0002-0826-8963

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The adaptive matched filter (AMF) is a method widely used in spectral unmixing to classify different tissue chromophores in photoacoustic images. However, a threshold needs to be applied to the AMF detection image to distinguish the desired tissue chromophores from the background. In this study, we propose an automatic threshold selection (ATS) algorithm capable of differentiating a target from the background, based on the features of the AMF detection image. The mean difference between the estimated thickness, using the ATS algorithm, and the known values was 0.17 SD (0.24) mm for the phantom inclusions and -0.05 SD (0.21) mm for the tissue samples of malignant melanoma. The evaluation shows that the thickness and the width of the phantom inclusions and the tumors can be estimated using AMF in an automatic way after applying the ATS algorithm.

Identifiers

PMID34457383
PMCPMC8367266

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.