Evidence map›Paper›PMID 34457311›Full record

ArticleRespirology case reports2021

Myelin basic protein expression in thymoma after methylprednisolone administration for multiple sclerosis.

Tomomi Isono, Naoko Ose, Keisuke Kawasaki, Ayumi Shibata, Soichiro Funaki, Yasushi Shintani

Open access · goldAbstract readCase Reports
In one paragraph

Article in Respirology case reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.1field-weighted citation impact, top 51% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Tomomi IsonoDepartment of General Thoracic Surgery Osaka University Graduate School of Medicine Osaka Japan.ORCID https://orcid.org/0000-0002-0652-2331
Naoko OseDepartment of General Thoracic Surgery Osaka University Graduate School of Medicine Osaka Japan.ORCID https://orcid.org/0000-0002-3509-9536
Keisuke KawasakiDepartment of Pathology Osaka University Graduate School of Medicine Osaka Japan.
Ayumi ShibataDepartment of General Thoracic Surgery Osaka University Graduate School of Medicine Osaka Japan.
Soichiro FunakiDepartment of General Thoracic Surgery Osaka University Graduate School of Medicine Osaka Japan.
Yasushi ShintaniDepartment of General Thoracic Surgery Osaka University Graduate School of Medicine Osaka Japan.
The University of Osaka · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The relationship between thymic epithelial tumour and demyelinating disease (DD) is unknown and surgical resection has not been optimized. A 39-year-old woman was administrated methylprednisolone for newly diagnosed multiple sclerosis. A thymic tumour was found in the antero-superior mediastinum via computed tomography of the chest. Video-assisted thoracoscopic thymectomy was performed. Histologically, the tumour was diagnosed as Type AB thymoma. Immunohistochemical staining showed positive myelin basic protein (MBP) in the cytosol of spindle cells in the tumour specimen. Germinal centres or lymphocytes infiltration were not noted. Ectopic MBP presentation in thymoma might be correlated with DD.

Indexed as

autoimmune diseasemultiple sclerosisthymomathymusvideo‐assisted thoracoscopic thymectomy

Identifiers

PMID34457311
PMCPMC8374605
OpenAlexW3195695830

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.