Evidence map›Paper›PMID 34457153›Full record

ArticleAMIA Joint Summits on Translational Science proceedings. AMIA Joint Summits on Translational Science

Privacy-preserving Sequential Pattern Mining in distributed EHRs for Predicting Cardiovascular Disease.

Eric W Lee, Li Xiong, Vicki Stover Hertzberg, Roy L Simpson, Joyce C Ho

Abstract read
In one paragraph

Article in AMIA Joint Summits on Translational Science proceedings. AMIA Joint Summits on Translational Science. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Review
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  3. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Eric W LeeDepartment of Computer Science, Emory University, Atlanta, GA.
Li XiongDepartment of Computer Science, Emory University, Atlanta, GA.
Vicki Stover HertzbergNell Hodgson Woodruff School of Nursing, Emory University, Atlanta, GA.
Roy L SimpsonNell Hodgson Woodruff School of Nursing, Emory University, Atlanta, GA.
Joyce C HoDepartment of Computer Science, Emory University, Atlanta, GA.

Funding

Implementing a Maternal health and PRegnancy Outcomes Vision for Everyone (IMPROVE)UL1TR002378 · NCATS · EMORY UNIVERSITY · PI Andres J Garcia, Elizabeth O. Ofili · 2017 to 2026
$92.1M
Decentralized differentially-private methods for dynamic data release and analysisR01GM118609 · NIGMS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI JIANG, XIAOQIAN, OHNO-MACHADO, LUCILA · 2017 to 2020
$2.3M
SCH: INT Re-envisioned Chat-assessment for Real-time Investigating of Nursing and Guidance R01LM013323 · NLM · EMORY UNIVERSITY · PI HERTZBERG, VICKI STOVER, HO, JOYCE C. · 2019 to 2022
$940k
Leveraging modern analytic approaches to improve diabetes outcomesK01LM012924 · NLM · EMORY UNIVERSITY · PI HO, JOYCE C. · 2018 to 2020
$545k
NCATS NIH HHS UL1 TR002378NIGMS NIH HHS R01 GM118609
6 · The paper itself

Abstract

From electronic health records (EHRs), the relationship between patients' conditions, treatments, and outcomes can be discovered and used in various healthcare research tasks such as risk prediction. In practice, EHRs can be stored in one or more data warehouses, and mining from distributed data sources becomes challenging. Another challenge arises from privacy laws because patient data cannot be used without some patient privacy guarantees. Thus, in this paper, we propose a privacy-preserving framework using sequential pattern mining in distributed data sources. Our framework extracts patterns from each source and shares patterns with other sources to discover discriminative and representative patterns that can be used for risk prediction while preserving privacy. We demonstrate our framework using a case study of predicting Cardiovascular Disease in patients with type 2 diabetes and show the effectiveness of our framework with several sources and by applying differential privacy mechanisms.

Indexed as

Cardiovascular DiseasesDiabetes Mellitus, Type 2ConfidentialityElectronic Health RecordsHumansPrivacy

Identifiers

PMID34457153
PMCPMC8378625

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.