Evidence map›Paper›PMID 34457142›Full record

ArticleAMIA Joint Summits on Translational Science proceedings. AMIA Joint Summits on Translational Science

Extracting Concepts for Precision Oncology from the Biomedical Literature.

Nicholas Greenspan, Yuqi Si, Kirk Roberts

Abstract read
In one paragraph

Article in AMIA Joint Summits on Translational Science proceedings. AMIA Joint Summits on Translational Science. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Nicholas GreenspanDepartment of Computer Science, Columbia University New York City NY, USA.
Yuqi SiSchool of Biomedical Informatics, The University of Texas Health Science Center at Houston Houston TX, USA.
Kirk RobertsSchool of Biomedical Informatics, The University of Texas Health Science Center at Houston Houston TX, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This paper describes an initial dataset and automatic natural language processing (NLP) method for extracting concepts related to precision oncology from biomedical research articles. We extract five concept types: Cancer, Mutation, Population, Treatment, Outcome. A corpus of 250 biomedical abstracts were annotated with these concepts following standard double-annotation procedures. We then experiment with BERT-based models for concept extraction. The best-performing model achieved a precision of 63.8%, a recall of 71.9%, and an F1 of 67.1. Finally, we propose additional directions for research for improving extraction performance and utilizing the NLP system in downstream precision oncology applications.

Indexed as

NeoplasmsHumansNatural Language ProcessingPrecision MedicinePublications

Identifiers

PMID34457142
PMCPMC8378653

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.