Evidence map›Paper›PMID 34457121›Full record

ArticleOxidative medicine and cellular longevity2021

The Emerging Role of Fatty Acid Synthase in Hypoxia-Induced Pulmonary Hypertensive Mouse Energy Metabolism.

Cuilan Hou, Juan Chen, Yuqi Zhao, Yanhua Niu, Shujia Lin, Shun Chen, Yanfang Zong, Xiaomin Sun, Lijian Xie, Tingting Xiao

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Oxidative medicine and cellular longevity, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
2.9field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 22 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Cuilan HouDepartment of Cardiology, Shanghai Children's Hospital, Shanghai Jiao Tong University, No. 355 Luding Road, Shanghai 200062, China.ORCID https://orcid.org/0000-0003-3972-1625
Juan ChenDepartment of Cardiology, Shanghai Children's Hospital, Shanghai Jiao Tong University, No. 355 Luding Road, Shanghai 200062, China.
Yuqi ZhaoDepartment of Cardiology, Shanghai Children's Hospital, Shanghai Jiao Tong University, No. 355 Luding Road, Shanghai 200062, China.
Yanhua NiuDepartment of Cardiology, Shanghai Children's Hospital, Shanghai Jiao Tong University, No. 355 Luding Road, Shanghai 200062, China.
Shujia LinDepartment of Cardiology, Shanghai Children's Hospital, Shanghai Jiao Tong University, No. 355 Luding Road, Shanghai 200062, China.
Shun ChenDepartment of Cardiology, Shanghai Children's Hospital, Shanghai Jiao Tong University, No. 355 Luding Road, Shanghai 200062, China.
Yanfang ZongDepartment of Cardiology, Shanghai Children's Hospital, Shanghai Jiao Tong University, No. 355 Luding Road, Shanghai 200062, China.
Xiaomin SunDepartment of Cardiology, Shanghai Children's Hospital, Shanghai Jiao Tong University, No. 355 Luding Road, Shanghai 200062, China.
Lijian XieDepartment of Cardiology, Shanghai Children's Hospital, Shanghai Jiao Tong University, No. 355 Luding Road, Shanghai 200062, China.ORCID https://orcid.org/0000-0002-0328-6820
Tingting XiaoDepartment of Cardiology, Shanghai Children's Hospital, Shanghai Jiao Tong University, No. 355 Luding Road, Shanghai 200062, China.ORCID https://orcid.org/0000-0001-7311-4496
Shanghai Jiao Tong University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimsThis study is aimed at examining whether fatty acid synthase (

resultsThe expression of

conclusionsInhibition of

Indexed as

Energy Metabolism4-ButyrolactoneAnimalsApoptosisFatty Acid SynthasesHypoxiaMiceMice, Inbred C57BLMitochondriaMyocytes, Smooth MusclePhosphatidylinositol 3-KinasesProto-Oncogene Proteins c-aktPulmonary Arterial HypertensionSignal Transduction4-Butyrolactone4-methylene-2-octyl-5-oxofuran-3-carboxylic acidFatty Acid SynthasesPhosphatidylinositol 3-KinasesProto-Oncogene Proteins c-akt

Identifiers

PMID34457121
PMCPMC8387195
OpenAlexW3196267090

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.