ReviewOxidative medicine and cellular longevity2021
Cognitive Dysfunction after Heart Disease: A Manifestation of the Heart-Brain Axis.
Review in Oxidative medicine and cellular longevity, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
22 citing papers in PubMed, 32 citations in OpenAlex.
- Effects of variation in exercise training load on cognitive performances and neurotrophic biomarkers in patients with coronary artery disease.Journal of applied physiology (Bethesda, Md. : 1985) · 2024Trial
- How organs react under fasting or glucose-insulin status: a self-controlled study usingEuropean journal of nuclear medicine and molecular imaging · 2026Article
- Methylglyoxal Accumulation is Associated with Brain Inflammation after Myocardial Infarction with Sex and Regional Differences.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- Advances in brain MRI for CAD-associated cognitive impairment with supplementary perspectives from traditional Chinese medicine.Frontiers in medicine · 2026Review
- Heterogeneous cognitive and neuroimaging profiles in older adults with type 2 diabetes: the modifying effect of coronary artery disease.Frontiers in aging neuroscience · 2026Article
- Bidirectional Interplay Between Traumatic Brain Injury and Cardiovascular Dysfunction in Athletes.Journal of clinical medicine · 2025Review
- Neurocognitive outcomes and memory transfer in heart transplantation.Global cardiology science & practice · 2025Review
- Observational protocol on neuropsychological disorders in cardiovascular disease for holistic prevention and treatment.Future cardiology · 2025Article
- Review
- Amyloid-β and heart failure in Alzheimer's disease: the new vistas.Frontiers in medicine · 2025Review
- Biological heart and brain ageing in subjects with cardiovascular diseases.Frontiers in cardiovascular medicine · 2025Article
- Trajectory of Cardiogenic Dementia: A New Perspective.Journal of cellular and molecular medicine · 2025Review
- Association between mild cognitive impairment and sleep quality in patients with chronic heart failure: a cross-sectional study.Frontiers in psychiatry · 2025Article
- Serum detection of blood brain barrier injury in subjects with a history of stroke and transient ischemic attack.JVS-vascular science · 2024Article
- Article
- Correlation between cognitive impairment and metabolic imbalance of gut microbiota in patients with schizophrenia.World journal of psychiatry · 2023Article
- The pathophysiology of cognitive impairment in individuals with heart failure: a systematic review.Frontiers in cardiovascular medicine · 2023Review
- At the heart of the matter: how mental stress and negative emotions affect atrial fibrillation.Frontiers in cardiovascular medicine · 2023Review
- Heart-brain axis: Association of congenital heart abnormality and brain diseases.Frontiers in cardiovascular medicine · 2023Review
- The Heart Is at Risk: Understanding Stroke-Heart-Brain Interactions with Focus on Neurogenic Stress Cardiomyopathy-A Review.Journal of stroke · 2023Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The functions of the brain and heart, which are the two main supporting organs of human life, are closely linked. Numerous studies have expounded the mechanisms of the brain-heart axis and its related clinical applications. However, the effect of heart disease on brain function, defined as the heart-brain axis, is less studied even though cognitive dysfunction after heart disease is one of its most frequently reported manifestations. Hypoperfusion caused by heart failure appears to be an important risk factor for cognitive decline. Blood perfusion, the immune response, and oxidative stress are the possible main mechanisms of cognitive dysfunction, indicating that the blood-brain barrier, glial cells, and amyloid-
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.