Evidence map›Paper›PMID 34457100›Full record

ArticleRadiology case reports2021

Pneumatosis cystoides intestinalis, a rare case in a pediatric patient following allogeneic hematopoietic stem cell transplantation: CT findings and literature review.

Diana Baldari, Paolo Pizzicato, Francesco Paolo Tambaro, Danilo De Novellis, Carmela Brillantino, Patrizia Lombardo, Luisa Castelli, Rocco Minelli, Massimo Zeccolini, Eugenio Rossi

Erratum issuedOpen access · goldAbstract readCase Reports
In one paragraph

Article in Radiology case reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.7field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 9 citations in OpenAlex.

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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Diana BaldariPausilipon Radiology Unit, Department of Health Services, A.O.R.N. Santobono-Pausilipon, Naples, Italy.
Paolo PizzicatoPausilipon Radiology Unit, Department of Health Services, A.O.R.N. Santobono-Pausilipon, Naples, Italy.
Francesco Paolo TambaroStem Cell Transplantation and Cell Therapy Unit, Pediatric Oncology Department, A.O.R.N. Santobono-Pausilipon, Naples, Italy.
Danilo De NovellisStem Cell Transplantation and Cell Therapy Unit, Pediatric Oncology Department, A.O.R.N. Santobono-Pausilipon, Naples, Italy.
Carmela BrillantinoPausilipon Radiology Unit, Department of Health Services, A.O.R.N. Santobono-Pausilipon, Naples, Italy.
Patrizia LombardoPausilipon Radiology Unit, Department of Health Services, A.O.R.N. Santobono-Pausilipon, Naples, Italy.
Luisa CastelliPausilipon Radiology Unit, Department of Health Services, A.O.R.N. Santobono-Pausilipon, Naples, Italy.
Rocco MinelliDepartment Life and Health "V. Tiberio", Univeristy of Molise, Campobasso, Italy.
Massimo ZeccoliniGeneral Radiology Unit, Department of Health Services, A.O.R.N. Santobono-Pausilipon, Naples, Italy.
Eugenio RossiPausilipon Radiology Unit, Department of Health Services, A.O.R.N. Santobono-Pausilipon, Naples, Italy.
Santobono Children's Hospital · ITUniversity of Campania "Luigi Vanvitelli" · ITUniversity of Molise · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Pneumatosis cystoides intestinalis (PCI) is a rare condition characterized by the presence of gas-filled cysts in the subserosa or submucosa of the bowel wall. It is associated with various disorders including chronic obstructive pulmonary diseases, autoimmune disorders, and organ transplantation. PCI has also been observed following Hematopoietic Stem Cell Transplantation (HSCT), associated with chemotherapy, acute Graft versus Host Disease (GvHD), immunosuppression, and infections. Computed tomography (CT) provides an easy diagnosis because it highlights the presence of air bubbles in the intestinal wall and possible pneumoperitoneum. We report the case of a patient with severe acquired medullary aplasia undergoing allogeneic HSCT with subsequent development of cutaneous GvHD and an incidental finding of PCI during a CT scan of the chest in absence of gastrointestinal symptoms. Our work aims at clarifying a possible complication in pediatric patients undergoing HSCT to guide young or non-pediatric radiologists in the identification of this rare condition, helping the clinician in the correct conservative management of these patients and reserving the surgical treatment only to specific complications.

Indexed as

BowelCTHSCTPneumatosis cytosides intestinalis

Identifiers

PMID34457100
PMCPMC8377547
OpenAlexW3195200635

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.