Observational studyDisease markers2021
Biomarkers of Inflammation and Inflammation-Related Indexes upon Emergency Department Admission Are Predictive for the Risk of Intensive Care Unit Hospitalization and Mortality in Acute Poisoning: A 6-Year Prospective Observational Study.
Observational study in Disease markers, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
13 citing papers in PubMed, 28 citations in OpenAlex.
- Development and validation of a prediction model for in-hospital mortality in older adults with acute poisoning.The Journal of international medical research · 2025Article
- Associations between the red blood cell distribution width and 30-day mortality in critically ill patients with delirium: a retrospective study using the MIMIC-IV database.Frontiers in aging neuroscience · 2025Article
- Association of the Cumulative Inflammatory Index and Long-Term Mortality in Stroke-Associated Pneumonia.Journal of inflammation research · 2025Article
- Evaluation of Biologics ACE2/Ang(1-7) Encapsulated in Plant Cells for FDA Approval: Safety and Toxicology Studies.Pharmaceutics · 2024Article
- Neutrophil-to-lymphocyte and platelet-to-lymphocyte ratios as mortality predictors in acute Aluminum phosphide (grain pills) poisoning: clinical insights and risk assessment.Toxicology research · 2024Article
- Electrocardiogram Features in Non-Cardiac Diseases: From Mechanisms to Practical Aspects.Journal of multidisciplinary healthcare · 2024Review
- Association of Hematological Biomarkers of Inflammation with 10-Year Major Adverse Cardiovascular Events and All-Cause Mortality in Patients with Metabolic Dysfunction-Associated Steatotic Liver Disease: The ARIC Study.Journal of inflammation research · 2024Article
- Gender Differences and Amputation Risk in Peripheral Artery Disease-A Single-Center Experience.Diagnostics (Basel, Switzerland) · 2023Article
- A nomogram proposal for early prediction of intensive care unit admission in patients with acute antipsychotic poisoning.Toxicology research · 2023Article
- Neutrophil-to-lymphocyte Ratio and Platelet-to-lymphocyte Ratio in the Patients with Euthyroid Hashimoto's Thyroiditis.Medeniyet medical journal · 2023Article
- Severe Intentional Corrosive (Nitric Acid) Acute Poisoning: A Case Report and Literature Review.Journal of personalized medicine · 2023Review
- Hematological indices as indicators of inflammation induced by exposure to pesticides.Environmental science and pollution research international · 2023Article
- The Value of Early and Follow-Up Elevated Scores Based on Peripheral Complete Blood Cell Count for Predicting Adverse Outcomes in COVID-19 Patients.Journal of personalized medicine · 2022Article
Corrections and comments
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Authors and funding
9 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Patients poisoned with drugs and nonpharmaceutical substances are frequently admitted from the emergency department (ED) to a medical or ICU department. We hypothesized that biomarkers of inflammation and inflammation-related indexes based on the complete blood cell (CBC) count can identify acutely poisoned patients at increased risk for ICU hospitalization and death. We performed a 6-year prospective cohort study on 1548 adult patients. The demographic data, the levels of hs-CRP (high-sensitivity C-reactive protein), CBC, and inflammation-related indexes based on CBC counts were collected upon admission and compared between survivors and nonsurvivors, based on the poison involved. Both a multivariate logistic regression model with only significant univariate predictors and a model including univariate predictors plus each log-transformed inflammation-related indexes for mortality were constructed. The importance of the variables for mortality was graphically represented using the nomogram. hs-CRP (odds ratio (OR), 1.38; 95% CI, 1.16-1.65,
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.