Evidence map›Paper›PMID 34456927›Full record

ArticleFrontiers in immunology2021

G6pd-Deficient Mice Are Protected From Experimental Cerebral Malaria and Liver Injury by Suppressing Proinflammatory Response in the Early Stage of

Haoan Yi, Weiyang Jiang, Fang Yang, Fan Li, Yirong Li, Wenjing Zhu, Qing Li, Syed Hassam Fakhar, Yaming Cao, Lan Luo and 2 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.7field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 7 citations in OpenAlex.

  1. Human genetic variations conferring resistance to malaria.Journal of translational medicine · 2025
    Review
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  3. Review
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  5. Increased Neutrophil HResearch square · 2024
    Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 1 country.

Haoan YiDepartment of Cell Biology and Medical Genetics, Kunming Medical University, Kunming, China.
Weiyang JiangDepartment of Cell Biology and Medical Genetics, Kunming Medical University, Kunming, China.
Fang YangDepartment of Cell Biology and Medical Genetics, Kunming Medical University, Kunming, China.
Fan LiDepartment of Pathology and Pathophysiology, Kunming Medical University, Kunming, China.
Yirong LiSchool of Pharmaceutical Sciences and Yunnan Key Laboratory of Pharmacology for Natural Products, Kunming Medical University, Kunming, China.
Wenjing ZhuDepartment of Human Anatomy/Histology and Embryology, School of Basic Medicine, Kunming Medical University, Kunming, China.
Qing LiDepartment of Cell Biology and Medical Genetics, Kunming Medical University, Kunming, China.
Syed Hassam FakharSchool of Public Health, Kunming Medical University, Kunming, China.
Yaming CaoDepartment of Immunology, College of Basic Medical Sciences, China Medical University, Shenyang, China.
Lan LuoDepartment of Cell Biology and Medical Genetics, Kunming Medical University, Kunming, China.
Wen ZhangDepartment of Cell Biology and Medical Genetics, Kunming Medical University, Kunming, China.
Yongshu HeDepartment of Cell Biology and Medical Genetics, Kunming Medical University, Kunming, China.
Kunming Medical University · CNChina Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Epidemiological studies provide compelling evidence that glucose-6-phosphate dehydrogenase (G6PD) deficiency individuals are relatively protected against

Indexed as

AnimalsBiomarkersBiopsyBlood-Brain BarrierCytokinesDisease Models, AnimalDisease SusceptibilityEnzyme ActivationGene Expression ProfilingGlucosephosphate DehydrogenaseGlucosephosphate Dehydrogenase DeficiencyHemolysisInflammation MediatorsLiver Diseases, ParasiticMalaria, CerebralMiceBiomarkersCytokinesGlucosephosphate DehydrogenaseInflammation Mediatorsacute liver injuryexperimental cerebral malariaG6PD deficiencyPlasmodium bergheiproinflammatory response

Identifiers

PMID34456927
PMCPMC8386684
OpenAlexW3195592869

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.