Evidence map›Paper›PMID 34456878›Full record

Observational studyFrontiers in endocrinology2021

Diabetes in Patients With Heart Failure With Reduced Ejection Fraction During Hospitalization: A Retrospective Observational Study.

Yiling Zhou, Miye Wang, Si Wang, Nan Li, Shengzhao Zhang, Siqi Tang, Qingyang Shi, Yuliang Zhao, Jingwen Li, Yuping Zeng and 4 more

Open access · goldAbstract readObservational Study
PubMed Full text at PMC Publisher
In one paragraph

Observational study in Frontiers in endocrinology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.5field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 11 citations in OpenAlex.

  1. Review
  2. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 3 institutions in 1 country.

Yiling ZhouDepartment of Endocrinology and Metabolism, West China Hospital, Sichuan University, Chengdu, China.
Miye WangThe Informatic Center, West China Hospital, Sichuan University, Chengdu, China.
Si WangDepartment of Cardiology, West China Hospital, Sichuan University, Chengdu, China.
Nan LiThe Informatic Center, West China Hospital, Sichuan University, Chengdu, China.
Shengzhao ZhangDepartment of Pharmacy, West China Hospital, Sichuan University, Chengdu, China.
Siqi TangDepartment of Cardiology, West China Hospital, Sichuan University, Chengdu, China.
Qingyang ShiChinese Evidence-based Medicine Center, Cochrane China Center and MAGIC China Center, West China Hospital, Sichuan University, Chengdu, China.
Yuliang ZhaoDivision of Nephrology, Kidney Research Institute, West China Hospital, Sichuan University, Chengdu, China.
Jingwen LiDepartment of Health Care Associated Infection Management, West China Hospital, Sichuan University, Chengdu, China.
Yuping ZengDepartment of Laboratory Medicine, West China Hospital, Sichuan University, Chengdu, China.
Huan SongWest China Biomedical Big Data Center, West China Hospital, Sichuan University, Chengdu, China.
Haoming TianDepartment of Endocrinology and Metabolism, West China Hospital, Sichuan University, Chengdu, China.
Shuangqing LiDepartment of General Medicine, West China Hospital, Sichuan University, Chengdu, China.
Sheyu LiDepartment of Endocrinology and Metabolism, West China Hospital, Sichuan University, Chengdu, China.
Sichuan University · CNWest China Hospital of Sichuan University · CNWest China Medical Center of Sichuan University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Diabetes is prevalent worldwide including hospitalized patients with heart failure with reduced ejection fraction (HFrEF). This retrospective study investigated the association of diabetes with in-hospital adverse events in patients with HFrEF. Methods: We analyzed data from electronic medical records of patients hospitalized with HFrEF in West China Hospital of Sichuan University from January 1, 2011, to September 30, 2018. Propensity score matching balances the baseline characteristics between patients with and without diabetes. Logistic and Poisson regressions investigated the association of diabetes with risks of intubation, cardiogenic shock, acute kidney injury (AKI), intensive care unit (ICU) admission and death during hospitalization, and length of ICU and hospital stay in the matched cases. Results: Among 6,022 eligible patients (including 1,998 with diabetes), 1,930 patient pairs with and without diabetes were included by propensity score matching. Patients with diabetes had a significantly increased risk of intubation (odds ratio [OR], 2.69; 95% confidence interval [CI], 2.25-3.22; Conclusions: Among patients with HFrEF, those with diabetes have a worse prognosis, including a higher risk of in-hospital intubation, cardiogenic shock, AKI, ICU admission and death during hospitalization, and longer ICU and hospital stay.

Indexed as

Acute Kidney InjuryAdultAgedCase-Control StudiesChinaDiabetes MellitusDiabetic AngiopathiesFemaleHeart FailureHospitalizationHospital MortalityHumansIntensive Care UnitsLength of StayMaleMiddle Agedacute kidney injurycardiogenic shockdiabetesHFrEFhospitalizationICUintubationlength of stay

Identifiers

PMID34456878
PMCPMC8387582
OpenAlexW3190434753

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.