SynthesisFrontiers in endocrinology2021
Outcomes of Minimally Invasive Thyroid Surgery - A Systematic Review and Meta-Analysis.
Synthesis in Frontiers in endocrinology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 54 papers, 3 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
54 citing papers in PubMed, 3 syntheses or guidelines pooled it, 99 citations in OpenAlex.
- A systematic review and meta-analysis: surgical outcomes comparing transoral robotic and open approaches to thyroidectomy.Journal of robotic surgery · 2026Pooled it
- No Change in Complications Following Thyroidectomy Despite Increase in Thyroid Cancer Surgeries: A Meta-Regression Analysis.Yonsei medical journal · 2024Pooled it
- Optimal primary wound closure methods after thyroid and parathyroid surgery: network meta-analysis of randomized clinical trials.BJS open · 2023Pooled it
- Endoscopic thyroidectomy via the submental approach: a balanced approach to aesthetics, safety, and recovery- a case series study.Frontiers in endocrinology · 2025Trial
- Global research landscape and emerging trends in robotic thyroid and neck surgery: a bibliometric and knowledge-mapping analysis.Journal of robotic surgery · 2026Article
- Article
- Minimally invasive video-assisted thyroidectomy (MIVAT) and thyroid cancer: a single centre 10-year follow-up.Gland surgery · 2026Article
- A decade-long shift in use of energy devices for BABA robotic thyroidectomy: automated video analysis by deep learning.Journal of robotic surgery · 2026Article
- Superior spinal accessory nerve function after robotic versus open selective neck dissection in papillary thyroid carcinoma: a retrospective and prospective cohort study.Journal of robotic surgery · 2026Article
- Robotic thyroidectomy using the da Vinci SP surgical system.Surgical endoscopy · 2026Review
- Transaxillary Robotic Thyroidectomy: A Novel Technique and Update.Journal of clinical medicine · 2026Review
- Comparing trans-oral endoscopic thyroidectomy vestibular approach and trans-areolar approaches regarding postoperative infections and swallowing difficulty.World journal of clinical cases · 2026Article
- Did scarless thyroidectomy meet expectations? An evaluation in the aspect of cosmesis: A single-centre prospective study.Journal of minimal access surgery · 2026Article
- Lateral mini-incision via cervical midline approach versus traditional incision for unilateral thyroid cancer: a retrospective cohort study.Frontiers in surgery · 2026Article
- Pan-immune inflammation value and system inflammation response index associated with prolonged hospital stay of thyroid nodule patients undergoing ultrasound-guided microwave ablation, both aged ≤55 years and > 55 years.Frontiers in endocrinology · 2026Article
- Global burden of thyroid cancer attributable to metabolic risk factors in women of reproductive age (20-49 years): a GBD 2021 cross-national analysis with projections to 2050.BMC women's health · 2025Article
- Safety and cosmetic results of trans-submental endoscopic thyroidectomy.Scientific reports · 2025Article
- Application effect of supportive psychological nursing combined with continuous nursing in patients with thyroid malignancy undergoing surgery.Scientific reports · 2025Article
- Changes in thyroid surgery over last 25 years.Scientific reports · 2025Article
- Use of technologies in thyroid surgery: Latin American Thyroid Society Surgical Affairs Committee Expert Opinion. Part 1.Archives of endocrinology and metabolism · 2025Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Purpose: Conventional thyroidectomy has been standard of care for surgical thyroid nodules. For cosmetic purposes different minimally invasive and remote-access surgical approaches have been developed. At present, the most used robotic and endoscopic thyroidectomy approaches are minimally invasive video assisted thyroidectomy (MIVAT), bilateral axillo-breast approach endoscopic thyroidectomy (BABA-ET), bilateral axillo-breast approach robotic thyroidectomy (BABA-RT), transoral endoscopic thyroidectomy Methods: A systematic search was conducted in Medline, Embase and Web of Science to identify original articles investigating operating time, length of hospital stay and complication rates regarding recurrent laryngeal nerve injury and hypocalcemia, of the different minimally invasive techniques. Results: Out of 569 identified manuscripts, 98 studies met the inclusion criteria. Most studies were retrospective in nature. The results of the systematic review varied. Thirty-one articles were included in the meta-analysis. Compared to the standard of care, the meta-analysis showed no significant difference in length of hospital stay, except a longer stay after BABA-ET. No significant difference in incidence of recurrent laryngeal nerve injury and hypocalcemia was seen. As expected, operating time was significantly longer for most minimally invasive techniques. Conclusions: This is the first comprehensive systematic review and meta-analysis comparing the eight most commonly used minimally invasive thyroid surgeries individually with standard of care. It can be concluded that minimally invasive techniques do not lead to more complications or longer hospital stay and are, therefore, not inferior to conventional thyroidectomy.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.