Evidence map›Paper›PMID 34456859›Full record

ArticleFrontiers in endocrinology2021

Association Between C-Peptide Level and Subclinical Myocardial Injury.

Ziwei Chen, Jing He, Qiang Ma, Mingbing Xiao

Open access · goldAbstract read
In one paragraph

Article in Frontiers in endocrinology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.9field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 11 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Ziwei ChenDepartment of Cardiology, Affiliated Hospital of Nantong University, Nantong, China.
Jing HeDepartment of Oncology, Affiliated Hospital of Nantong University, Nantong, China.
Qiang MaSchool of Public Health, Nantong University, Nantong, China.
Mingbing XiaoResearch Center of Clinical Research Center of Clinical Medicine, Affiliated Hospital of Nantong University, Nantong, China.
Affiliated Hospital of Nantong University · CNNantong University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Previous studies have confirmed an association between C-peptide levels with the risk of cardiometabolic diseases. However, whether circulating C-peptide was related to subclinical myocardial injury (SC-MI) remains unknown. Methods: A total of 3,752 participants without a history of cardiovascular diseases were included in our study from National Health and Nutrition Examination Survey III (NHANES III). Multivariable linear regression was performed to explore the correlation between C-peptide and cardiac injury score (CIIS). Multivariate logistic regression was used to examine the association between C-peptide quartile and SC-MI. Results: Circulating C-peptide was significantly associated with CIIS (β:0.09, 95% confidence interval [CI]: 0.00-0.17; Conclusions: The level of C-peptide was independently associated with CIIS and SC-MI, which could serve as a new risk factor of SC-MI.

Indexed as

AgedC-PeptideCross-Sectional StudiesElectrocardiographyFemaleHumansMaleMiddle AgedMyocardial InfarctionNutrition SurveysC-PeptideassociationC-peptidecross sectional studyNHANES IIIsubclinical cardiac injury

Identifiers

PMID34456859
PMCPMC8397456
OpenAlexW3190416205

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.