Evidence map›Paper›PMID 34456710›Full record

ArticleFrontiers in aging neuroscience2021

Cerebral Cortex Apoptosis in Early Aged Hypertension: Effects of Epigallocatechin-3-Gallate.

Min-Huang Hsieh, Zhen-Yang Cui, Ai-Lun Yang, Nguyen Thanh Nhu, Shih-Ying Ting, Shao-Hong Yu, Yu-Jung Cheng, Yi-Yuan Lin, Xu-Bo Wu, Shin-Da Lee

Open access · goldAbstract read
In one paragraph

Article in Frontiers in aging neuroscience, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.5field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 10 citations in OpenAlex.

  1. Nan fang yi ke da xue xue bao = Journal of Southern Medical University · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 7 institutions in 3 countries.

Min-Huang HsiehDivision of Endocrinology and Metabolism, Department of Internal Medicine, Jen-Ai Hospital, Taichung, Taiwan.
Zhen-Yang CuiSchool of Rehabilitation Medicine, Weifang Medical University, Shandong, China.
Ai-Lun YangInstitute of Sports Sciences, University of Taipei, Taipei, Taiwan.
Nguyen Thanh NhuFaculty of Medicine, Can Tho University of Medicine and Pharmacy, Can Tho, Vietnam.
Shih-Ying TingDepartment of Internal Medicine, Jen-Ai Hospital, Taichung, Taiwan.
Shao-Hong YuCollege of Rehabilitation, Shandong University of Traditional Chinese Medicine, Shandong, China.
Yu-Jung ChengDepartment of Physical Therapy, Graduate Institute of Rehabilitation Science, China Medical University, Taichung, Taiwan.
Yi-Yuan LinDepartment of Exercise and Health Science, National Taipei University of Nursing and Health Sciences, Taipei, Taiwan.
Xu-Bo WuDepartment of Rehabilitation, Seventh People's Hospital Affiliated to Shanghai University of Traditional Chinese Medicine, Shanghai, China.
Shin-Da LeeSchool of Rehabilitation Medicine, Weifang Medical University, Shandong, China.
China Medical University · TWJen-Ai Hospital · TWWeifang Medical University · CNNational Taipei University of Nursing and Health Science · TWShandong University of Traditional Chinese Medicine · CNShanghai University of Traditional Chinese Medicine · CNUniversity of Taipei · TW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study aimed to investigate cerebral cortex apoptosis on the early aged hypertension and the effects of green tea flavonoid epigallocatechin-3-gallate (EGCG). Twenty-four rats were divided into three groups: a control Wistar-Kyoto group (WKY,

Indexed as

caspase-independent apoptosisEGCGhypertensionneural apoptosisneural survival

Identifiers

PMID34456710
PMCPMC8397540
OpenAlexW3193757467

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.