Evidence map›Paper›PMID 34456185›Full record

ArticleAging2021

Association between housing type and accelerated biological aging in different sexes: moderating effects of health behaviors.

Ted Kheng Siang Ng, David Bruce Matchar, Timothy V Pyrkov, Peter O Fedichev, Angelique Wei-Ming Chan, Brian Kennedy

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Aging, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.7field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 8 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 5 institutions in 4 countries.

Ted Kheng Siang NgArizona State University, Edson College of Nursing and Health Innovation, Phoenix, AZ 85004, USA.
David Bruce MatcharDuke-National University of Singapore Medical School, Program in Health Services and Systems Research, Singapore.
Timothy V PyrkovGERO PTE. LTD., Singapore.
Peter O FedichevGERO PTE. LTD., Singapore.
Angelique Wei-Ming ChanDuke-National University of Singapore Medical School, Program in Health Services and Systems Research, Singapore.
Brian KennedyNational University of Singapore, Center for Healthy Longevity, Healthy Longevity Program and Department of Biochemistry, Yong Loo Lin School of Medicine, Singapore.
Geriatric Education and Research Institute · SGAgency for Science, Technology and Research · SGArizona State University · USDuke University · USNational University of Singapore · SG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionDespite associated with multiple geriatric disorders, whether housing type, an indicator of socioeconomic status (SES) and environmental factors, is associated with accelerated biological aging is unknown. Furthermore, although individuals with low-SES have higher body mass index (BMI) and are more likely to smoke, whether BMI and smoking status moderate the association between SES and biological aging is unclear. We examined these questions in urbanized low-SES older community-dwelling adults.

methodsFirst, we analyzed complete blood count data using the cox proportional hazards model and derived measures for biological age (BA) and biological age acceleration (BAA, the higher the more accelerated aging) (

resultsThere were significant differences between men and women in housing type and BAA. Compared to residents in ≥3 room public or private housing, older adults resided in 1-2 room public housing had a higher BAA. Furthermore, BMI attenuated the association between housing type and BAA. In sex-stratified analyses, the main and interaction effects were only significant in women. In men, smoking status instead aggravated the association between housing type and BAA.

conclusionControlling for other SES indicators, housing type is an independent socio-environmental determinant of BA and BAA in a low-SES urbanized population. There were also sex differences in the moderating effects of health behaviors on biological aging.

Indexed as

Health BehaviorHousingAgedAged, 80 and overAgingBody Mass IndexFemaleHumansMaleMiddle AgedSex FactorsSocial Classenvironmental factorgerosciencehealth disparitysocial determinant of healthsocioeconomic status

Identifiers

PMID34456185
PMCPMC8436907
OpenAlexW3198608037

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.