Evidence map›Paper›PMID 34455817›Full record

ReviewHypertension (Dallas, Tex. : 1979)2021

Beyond Atherosclerosis and Fibromuscular Dysplasia: Rare Causes of Renovascular Hypertension.

Alexandre Persu, Caitriona Canning, Aleksander Prejbisz, Piotr Dobrowolski, Laurence Amar, Constantina Chrysochou, Jacek Kądziela, Mieczysław Litwin, Daan van Twist, Patricia Van der Niepen and 5 more

Open access · bronzeAbstract readReview
In one paragraph

Review in Hypertension (Dallas, Tex. : 1979), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
3.1field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 35 citations in OpenAlex.

  1. Article
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  8. Review
  9. Management of Renovascular Hypertension and Renal Denervation in Patients with Hypertension: An Italian Nationwide Survey.High blood pressure & cardiovascular prevention : the official journal of the Italian Society of Hypertension · 2024
    Article
  10. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 11 institutions in 7 countries.

Alexandre Persu *Pole of Cardiovascular Research, Institut de Recherche Expérimentale et Clinique and Division of Cardiology, Cliniques Universitaires Saint-Luc, Université Catholique de Louvain, Brussels, Belgium (A.P.).ORCID 0000-0002-4007-9695
Caitriona Canning *Department of Vascular Medicine and Surgery, St. James's Hospital, Dublin, Ireland (C.C.).
Aleksander PrejbiszDepartment of Hypertension, National Institute of Cardiology, Warsaw, Poland (A.P., P.D., M.J., A.J.).ORCID 0000-0001-7085-0244
Piotr DobrowolskiDepartment of Hypertension, National Institute of Cardiology, Warsaw, Poland (A.P., P.D., M.J., A.J.).ORCID 0000-0002-8919-1661
Laurence AmarUniversité de Paris, INSERM CIC1418, France (L.A., M.A.).ORCID 0000-0003-3942-4276
Constantina ChrysochouRenal Department, Salford Royal NHS Foundation Trust, Manchester, United Kingdom (C.C.).ORCID 0000-0003-1966-5558
Jacek KądzielaDepartment of Interventional Cardiology and Angiology, National Institute of Cardiology, Warsaw, Poland (J.K.).
Mieczysław LitwinDepartment of Nephrology and Arterial Hypertension, The Children's Memorial Health Institute, Warsaw, Poland (M.L.).ORCID 0000-0002-5241-2483
Daan van TwistZuyderland Medical Centre, Sittard/Heerlen, the Netherlands (D.v.T.).
Patricia Van der NiepenDepartment of Nephrology and Hypertension, Vrije Universiteit Brussel, Universitair Ziekenhuis Brussel, Belgium (P.V.d.N.).ORCID 0000-0002-6401-1580
Gregoire WuerznerService of Nephrology and Hypertension, Lausanne University Hospital and University of Lausanne, Switzerland (G.W.).ORCID 0000-0002-6424-7630
Peter de LeeuwDepartment of Internal Medicine and Gastroenterology, Zuyderland Medical Center, Heerlen, the Netherlands (P.d.L.).ORCID 0000-0002-4949-5812
Michel AziziUniversité de Paris, INSERM CIC1418, France (L.A., M.A.).
Magda Januszewicz *Department of Hypertension, National Institute of Cardiology, Warsaw, Poland (A.P., P.D., M.J., A.J.).
Andrzej Januszewicz *Department of Hypertension, National Institute of Cardiology, Warsaw, Poland (A.P., P.D., M.J., A.J.).
Institute of Cardiology · PLInserm · FRChildren's Memorial Health Institute · PLCliniques Universitaires Saint-Luc · BEMaastricht University Medical Centre · NLMedical University of Warsaw · PLSalford Royal NHS Foundation Trust · GBSt. James's Hospital · IEUniversitair Ziekenhuis Brussel · BEUniversity of Lausanne · CHZuyderland Medisch Centrum · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Renovascular hypertension is one of the most common forms of secondary hypertension. Over 95% of cases of renovascular hypertension are due either to atherosclerosis of the main renal artery trunks or to fibromuscular dysplasia. These two causes of renal artery stenosis have been extensively discussed in recent reviews and consensus. The aim of the current article is to provide comprehensive and up-to-date information on the remaining causes. While these causes are rare or extremely rare, etiologic and differential diagnosis matters both for prognosis and management. Therefore, the clinician cannot ignore them. For didactic reasons, we have grouped these different entities into stenotic lesions (neurofibromatosis type 1 and other rare syndromes, dissection, arteritis, and segmental arterial mediolysis) often associated with aortic coarctation and other arterial abnormalities, and nonstenotic lesions, where hypertension is secondary to compression of adjacent arteries and changes in arterial pulsatility (aneurysm) or to the formation of a shunt, leading to kidney ischemia (arteriovenous fistula). Finally, thrombotic disorders of the renal artery may also be responsible for renovascular hypertension. Although thrombotic/embolic lesions do not represent primary vessel wall disease, they are characterized by frequent macrovascular involvement. In this review, we illustrate the most characteristic aspects of these different entities responsible for renovascular hypertension and discuss their prevalence, pathophysiology, clinical presentation, management, and prognosis.

Indexed as

Alagille SyndromeAortic DissectionAtherosclerosisFibromuscular DysplasiaHumansHypertension, RenovascularNeurofibromatosis 1Renal Artery ObstructionTakayasu Arteritisaneurysmarteriovenous fistuladissectionhypertension, renovascularneurofibromatosis 1

Identifiers

PMID34455817
PMCPMC8415524
OpenAlexW3198636938

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.