ArticleAnnals of geriatric medicine and research2021
Delirium in Frail Older Adults.
Article in Annals of geriatric medicine and research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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Who cites it
17 citing papers in PubMed, 28 citations in OpenAlex.
- Improving Delirium Prediction in Surgery: Enhanced Machine Learning Models vs. Traditional Risk Scores.Journal of Korean medical science · 2026Article
- Association of Frailty and Delirium with Hospitalization Outcomes Among Older Adults With Rheumatic Diseases.ACR open rheumatology · 2026Article
- Regional cerebral oxygen saturation metrics for predicting postoperative delirium in elderly patients undergoing non-cardiac, non-neurological surgery: a propensity-matched cohort study.Journal of anesthesia · 2026Article
- The perceptions of European geriatricians on the co-occurrence and links between dementia, delirium and frailty.European geriatric medicine · 2025Article
- Perioperative Risk Factors for Postoperative Delirium in Non-dementia Older Patients after Non-cardiac Surgery and Anesthesia: A Prospective Study.Annals of geriatric medicine and research · 2025Article
- Exploring Cognitive Stimulation as a Therapy for the Prevention of Delirium in a Hospital Setting: A Narrative Review.Behavioral sciences (Basel, Switzerland) · 2025Review
- Factors involved in the development of hospital-acquired conditions in older patients in acute care settings: a scoping review.BMC health services research · 2025Article
- Improved Systemic Inflammation is Associated with Functional Prognosis in Post-Stroke Patients.Annals of geriatric medicine and research · 2024Article
- Impact of Frailty and Delirium Among Older Adults Admitted With Acute Decompensated Heart Failure.JACC. Advances · 2024Article
- Causal relationships between delirium and Parkinson's disease: a bidirectional two-sample Mendelian randomization study.European journal of medical research · 2024Article
- Geriatric care-related outcomes in patients 75 years and older admitted to a pulmonary disease center and predictors for hospital-related complications.Aging medicine (Milton (N.S.W)) · 2023Article
- Is the clinical frailty scale feasible to use in an emergency department setting? A mixed methods study.BMC emergency medicine · 2023Observational
- Clostridium tetani Infection in a Geriatric Patient: Do Not Let Your Guard Off!Annals of geriatric medicine and research · 2023Article
- Association between frailty, delirium, and mortality in older critically ill patients: a binational registry study.Annals of intensive care · 2022Article
- Acute disease induced cognitive dysfunction in older patients - an unrecognized syndrome.BMC geriatrics · 2022Article
- Operationalization of the Clinical Frailty Scale in Korean Community-Dwelling Older People.Frontiers in medicine · 2022Article
- Frailty as a Clinically Relevant Measure of Human Aging.Annals of geriatric medicine and research · 2021Article
Corrections and comments
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Authors and funding
1 author at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Delirium and frailty are prevalent geriatric syndromes and important public health issues among older adults. The prevalence of delirium among hospitalized older adults ranges from 15% to 75%, while that of frailty ranges from 12% to 24%. The exact pathophysiology of these two conditions has not been clearly identified, although several hypotheses have been proposed. However, these conditions are considered to be multifactorial in etiology and are associated with inflammation related to aging, alterations in vascular systems, genetics, and nutritional deficiency. Furthermore, clinically, they are significantly associated with frailty, which increases the risk of delirium by almost two- to three-fold among hospitalized older adults. With their multifactorial etiology and unknown pathophysiology, current evidence supports more practical multicomponent patient-centered approaches to prevent and manage delirium with frailty among hospitalized older adults. These comprehensive and organized bundled approaches can identify high-risk patients with frailty and more effectively manage their delirium.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.