Evidence map›Paper›PMID 34455547›Full record

ArticleBrazilian journal of microbiology : [publication of the Brazilian Society for Microbiology]2021

Swine influenza A virus subtypes circulating in Brazilian commercial pig herds from 2012 to 2019.

Ana Luiza Soares Fraiha, Ana Carolina Diniz Matos, João Luis Reis Cunha, Beatriz Senra Álvares da Silva Santos, Maria Vitória Chaves Peixoto, Anna Gabriella Guimarães Oliveira, Grazielle Cossenzo Florentino Galinari, Heloíza Irtes de Jesus Nascimento, Maria Isabel Maldonado Coelho Guedes, Alexandre de Magalhães Vieira Machado and 2 more

Open access · bronzeAbstract read
In one paragraph

Article in Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology], 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.6field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 10 citations in OpenAlex.

  1. Passive surveillance for Influenza A virus among swine, Brazil, 2009-2023.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 1 country.

Ana Luiza Soares FraihaLaboratório de Pesquisa em Virologia Animal, Departamento de Medicina Veterinária Preventiva, Universidade Federal de Minas Gerais, Escola de Veterinária - Campus Pampulha da, Av. Pres. Antônio Carlos, 6627 - São Luiz, Belo Horizonte, MG, 31270-901, Brazil.ORCID https://orcid.org/0000-0003-2100-8696
Ana Carolina Diniz MatosLaboratório de Pesquisa em Virologia Animal, Departamento de Medicina Veterinária Preventiva, Universidade Federal de Minas Gerais, Escola de Veterinária - Campus Pampulha da, Av. Pres. Antônio Carlos, 6627 - São Luiz, Belo Horizonte, MG, 31270-901, Brazil.ORCID https://orcid.org/0000-0003-3175-2590
João Luis Reis CunhaDepartamento de Medicina Veterinária Preventiva, Universidade Federal de Minas Gerais, Belo Horizonte, MG, Brazil.ORCID https://orcid.org/0000-0003-1034-0992
Beatriz Senra Álvares da Silva SantosLaboratório de Pesquisa em Virologia Animal, Departamento de Medicina Veterinária Preventiva, Universidade Federal de Minas Gerais, Escola de Veterinária - Campus Pampulha da, Av. Pres. Antônio Carlos, 6627 - São Luiz, Belo Horizonte, MG, 31270-901, Brazil.ORCID https://orcid.org/0000-0002-1497-4397
Maria Vitória Chaves PeixotoLaboratório de Pesquisa em Virologia Animal, Departamento de Medicina Veterinária Preventiva, Universidade Federal de Minas Gerais, Escola de Veterinária - Campus Pampulha da, Av. Pres. Antônio Carlos, 6627 - São Luiz, Belo Horizonte, MG, 31270-901, Brazil.ORCID https://orcid.org/0000-0003-1856-486X
Anna Gabriella Guimarães OliveiraDepartamento de Medicina Veterinária Preventiva, Universidade Federal de Minas Gerais, Belo Horizonte, MG, Brazil.ORCID https://orcid.org/0000-0003-4511-3722
Grazielle Cossenzo Florentino GalinariLaboratório de Pesquisa em Virologia Animal, Departamento de Medicina Veterinária Preventiva, Universidade Federal de Minas Gerais, Escola de Veterinária - Campus Pampulha da, Av. Pres. Antônio Carlos, 6627 - São Luiz, Belo Horizonte, MG, 31270-901, Brazil.ORCID https://orcid.org/0000-0003-3823-231X
Heloíza Irtes de Jesus NascimentoLaboratório de Pesquisa em Virologia Animal, Departamento de Medicina Veterinária Preventiva, Universidade Federal de Minas Gerais, Escola de Veterinária - Campus Pampulha da, Av. Pres. Antônio Carlos, 6627 - São Luiz, Belo Horizonte, MG, 31270-901, Brazil.ORCID https://orcid.org/0000-0002-5694-2932
Maria Isabel Maldonado Coelho GuedesLaboratório de Pesquisa em Virologia Animal, Departamento de Medicina Veterinária Preventiva, Universidade Federal de Minas Gerais, Escola de Veterinária - Campus Pampulha da, Av. Pres. Antônio Carlos, 6627 - São Luiz, Belo Horizonte, MG, 31270-901, Brazil.ORCID https://orcid.org/0000-0002-6734-0216
Alexandre de Magalhães Vieira MachadoLaboratório de Imunologia de Doenças Virais, Instituto de Pesquisa René Rachou, Fundação Oswaldo Cruz, Belo Horizonte, MG, Brazil.ORCID https://orcid.org/0000-0003-1506-4093
Erica Azevedo CostaLaboratório de Pesquisa em Virologia Animal, Departamento de Medicina Veterinária Preventiva, Universidade Federal de Minas Gerais, Escola de Veterinária - Campus Pampulha da, Av. Pres. Antônio Carlos, 6627 - São Luiz, Belo Horizonte, MG, 31270-901, Brazil.ORCID https://orcid.org/0000-0002-5396-3818
Zélia Inês Portela LobatoLaboratório de Pesquisa em Virologia Animal, Departamento de Medicina Veterinária Preventiva, Universidade Federal de Minas Gerais, Escola de Veterinária - Campus Pampulha da, Av. Pres. Antônio Carlos, 6627 - São Luiz, Belo Horizonte, MG, 31270-901, Brazil. ziplobato@gmail.com.ORCID http://orcid.org/0000-0002-9399-3691
Universidade Federal de Minas Gerais · BRFundação Oswaldo Cruz · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The swine influenza A virus (SIAV) subtypes/lineages H1N1pdm09, H3N2, H1N2, and H1N1 of seasonal human origin are widespread in Brazilian swine herds. A monovalent inactivated H1N1pdm09 vaccine was licensed in Brazil in 2014. However, there are concerns about its efficacy due to the limited vaccine cross-protection against heterologous viruses and the potential for exacerbated reactions against vaccine strains. Thus, monitoring SIAVs subtypes/lineages that are circulating in the Brazilian swine population is important, by applying a fast and efficient diagnostic test in herd field samples. A RT-PCR assay was developed, using primers specific for HA subtyping of Brazilian SIAV, and was used to evaluate the occurrence of subtypes from samples collected between 2012 and 2019. From 167 field samples positive for influenza A, 117 were subtyped by nested RT-PCR assay. A higher occurrence of H1N1pdm was observed from 2012 to 2015, H3N2 in 2017, and H1hu in 2017 to 2019. A hemagglutination inhibition test was performed in serum samples received from 2017 to 2019, confirming these data. The molecular data highlights the importance of H1hu and H3N2 detection since there are no vaccines available for the subtypes/lineages and raises an alert of H1hu for its potential to infect humans. Serological data suggest a cyclical profile of occurrence between the H3N2 and H1N1pdm over time. Monitoring SIAVs circulating in Brazilian swine herds is necessary, which provides the relevant information for field veterinarians to apply effective control measures on the properties.

Indexed as

Influenza A Virus, H1N1 SubtypeInfluenza A Virus, H3N2 SubtypeOrthomyxoviridae InfectionsSwine DiseasesAnimalsBrazilSwineBrazilGenotypingH1huH1N1pdmH3N2Influenza virusSerologySwine

Identifiers

PMID34455547
PMCPMC8402972
OpenAlexW3196723302

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.