Evidence map›Paper›PMID 34455515›Full record

ArticleMikrochimica acta2021

A highly sensitive dual-read assay using nitrogen-doped carbon dots for the quantitation of uric acid in human serum and urine samples.

Fan Li, Jiahan Rui, Ziyu Yan, Ping Qiu, Xiaomin Tang

Open access · bronzeAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Mikrochimica acta, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
2.7field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 45 citations in OpenAlex.

  1. Review
  2. Uric acid detectionRSC advances · 2025
    Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Fan LiDepartment of Chemistry, Nanchang University, Nanchang, 330031, China.
Jiahan RuiDepartment of Chemistry, Nanchang University, Nanchang, 330031, China.
Ziyu YanDepartment of Chemistry, Nanchang University, Nanchang, 330031, China.
Ping QiuDepartment of Chemistry, Nanchang University, Nanchang, 330031, China. pingqiu@ncu.edu.cn.ORCID http://orcid.org/0000-0003-1680-6378
Xiaomin TangThe Fourth Affiliated Hospital, Nanchang University, Nanchang, 330003, China.
Nanchang University · CN

Funding

National Natural Science Foundation of China 21765015National Natural Science Foundation of China 21808099Science and Technology Innovation Platform of Jiangxi Province 20192BCD40001
6 · The paper itself

Abstract

A simple dual-read assay for uric acid (UA) was developed based on a combined ratiometric fluorescent and colorimetric strategy using nitrogen-doped carbon dots (N-CDs). The biosensor relies on the oxidation of UA by uricase to produce H

Indexed as

Biosensing TechniquesCarbonColorimetryFluorescent DyesHumansHydrogen PeroxideLimit of DetectionNitrogenPhenylenediaminesQuantum DotsSpectrometry, FluorescenceUrate OxidaseUric Acid1,2-diaminobenzeneCarbonFluorescent DyesHydrogen PeroxideNitrogenPhenylenediaminesUrate OxidaseUric AcidDual-mode detectionIodide-peroxidase-like activityNitrogen-doped carbon dotsO-PhenylenediamineSerum and urine samplesUric acid

Identifiers

PMID34455515
PMCPMC8403067
OpenAlexW3196462059

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.