Evidence map›Paper›PMID 34455463›Full record

ReviewRheumatology international2021

COVID-19 and fertility-at the crossroads of autoimmunity and thrombosis.

Javeria Tariq, Tulika Chatterjee, Laura Andreoli, Latika Gupta

Open access · bronzeAbstract readReview
In one paragraph

Review in Rheumatology international, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
1.1field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it, 7 citations in OpenAlex.

  1. Impact of COVID-19 on fertility and assisted reproductive technology (ART): a systematic review.Romanian journal of morphology and embryology = Revue roumaine de morphologie et embryologie
    Pooled it
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 4 institutions in 4 countries.

Javeria TariqMedical College, The Aga Khan University, National Stadium Road, Karachi, 74800, Pakistan.ORCID http://orcid.org/0000-0001-9771-9449
Tulika ChatterjeeDepartment of Internal Medicine, University of Illinois, College of Medicine at Peoria, 530 NE Glen Oak Ave, Peoria, IL, 61637, USA.ORCID https://orcid.org/0000-0001-8844-851X
Laura AndreoliUnit of Rheumatology and Clinical Immunology, ASST Spedali Civili, Department of Clinical and Experimental Sciences, University of Brescia, Piazzale Spedali Civili 1, 25123, Brescia, Italy.ORCID http://orcid.org/0000-0002-9107-3218
Latika GuptaDepartment of Clinical Immunology and Rheumatology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Raebareli Road, Lucknow, 226014, India. drlatikagupta@gmail.com.ORCID http://orcid.org/0000-0003-2753-2990
Aga Khan University · PKAzienda Socio Sanitaria Territoriale degli Spedali Civili di Brescia · ITSanjay Gandhi Post Graduate Institute of Medical Sciences · INUniversity of Illinois Urbana-Champaign · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The SARS-CoV-2 virus is known to mediate attack via ACE-2 Receptor, thus having adverse effects on cardiovascular, respiratory, digestive and reproductive systems, the latter being an area of emerging concern, due to the associated impact on fertility, with potential for an outsized effect on population distribution and socioeconomic road map in subsequent years. This narrative review aims to put forth the current evidence of effect of SARS-CoV-2 on human fertility from a multipronged immunologic, haematologic, and gynaecologic perspective; highlighting the areas of contradiction and potential future measures. A literature search was conducted through the MEDLINE and SCOPUS databases to identify articles on the subject in English. Relevant information was extracted from around 300 articles for this review. The existing data give non-conclusive evidence about the impact of SARS-CoV-2 infection on fertility; however, a greater impact on male fertility as compared to females merits further exploration. However, reproduction and fertility is a key concern and considering the pandemic is prolonged, natural conception or ART require extra precautions.

Indexed as

AutoimmunityFertilityAngiotensin-Converting Enzyme 2COVID-19FemaleGenitaliaHumansMalePandemicsPregnancySARS-CoV-2ACE2 protein, humanAngiotensin-Converting Enzyme 2AutoimmunityCOVID-19Female fertilityMale fertilitySexual/vertical transmission

Identifiers

PMID34455463
PMCPMC8402971
OpenAlexW3198559620

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.