Evidence map›Paper›PMID 34454627›Full record

ArticleTropical medicine and health2021

Diabetes mellitus and HIV infection among active tuberculosis patients in Northwest Ethiopia: health facility-based cross-sectional study.

Begna Tulu, Eden Amsalu, Yohannes Zenebe, Melkamu Abebe, Yeshimebet Fetene, Manamnot Agegn, Alemayehu Abate, Keerati Ponpetch, Teshome Bekana, Balako Gumi and 1 more

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Article in Tropical medicine and health, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

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0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

  1. Key risk factors for pulmonary vs. extrapulmonary tuberculosis: a comparative study in Southwest Ethiopia.Journal of clinical tuberculosis and other mycobacterial diseases · 2026
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4 · The record

Corrections and comments

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5 · Who and what money

Authors and funding

11 authors.

Begna TuluDepartment of Medical Laboratory Sciences, Bahir Dar University, Bahir Dar, Ethiopia. tulubegna@gmail.com.ORCID http://orcid.org/0000-0003-1341-9559
Eden AmsaluDepartment of Pediatric Nursing, Bahir Dar University, Bahir Dar, Ethiopia.
Yohannes ZenebeDepartment of Medical Laboratory Sciences, Bahir Dar University, Bahir Dar, Ethiopia.
Melkamu AbebeDepartment of Pediatric Nursing, Bahir Dar University, Bahir Dar, Ethiopia.
Yeshimebet FeteneDepartment of Pediatric Nursing, Bahir Dar University, Bahir Dar, Ethiopia.
Manamnot AgegnDepartment of Pediatric Nursing, Bahir Dar University, Bahir Dar, Ethiopia.
Alemayehu AbateDepartment of Pediatric Nursing, Bahir Dar University, Bahir Dar, Ethiopia.
Keerati PonpetchSirindhorn College of Public Health Trang, Faculty of Public Health and Allied Health Sciences, Praboromarajchanok Institute, Ministry of Public Health, Nonthaburi, Thailand.
Teshome BekanaAklilu Lemma Institute of Pathobiology, Addis Ababa University, PO Box 1176, Addis AbabaAddis Ababa, Ethiopia.
Balako GumiAklilu Lemma Institute of Pathobiology, Addis Ababa University, PO Box 1176, Addis AbabaAddis Ababa, Ethiopia.
Gobena AmeniAklilu Lemma Institute of Pathobiology, Addis Ababa University, PO Box 1176, Addis AbabaAddis Ababa, Ethiopia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe prevalence of diabetes mellitus (DM) is increasing globally and its comorbidity with tuberculosis (TB) is re-emerging, especially in low- and middle-income countries.

objectiveThe main aim of this study is to determine the prevalence of DM and HIV infection and their associated risk factors among active tuberculosis patients in Northwest Ethiopia.

methodsThis hospital-based cross-sectional study was conducted between February 1st and June 30th, 2017 among active TB patients in two hospitals of Northwest Ethiopia. Two hundred and sixty-seven active TB cases aged 18 years or older were screened for diabetes using fasting blood glucose (FBG) test. Semi-structured questionnaires were used to collect demographic data, lifestyle habits and clinical data. Identification of pre-diabetes or diabetes in TB patients was achieved according to American Diabetes Association guidelines (2016).

resultsPrevalence of DM and TB comorbidity was 11.5% (95% confidence interval, CI 7.8-15.2) compared to 24.9% (95% CI 20.1-30.1) for pre-diabetes. Prevalence of HIV/TB co-infection was 21.9% (95% CI 16.7-26.8). Risk of DM was higher in TB patients from a rural location (adjusted odds ratio, aOR 3.13, 95% CI 1.02-9.62, p = 0.046). Similarly, DM was higher in TB patients who have a family history of DM (aOR 4.54, 95% CI 1.31-15.68, p = 0.017). Furthermore, HIV/TB co-infection was identified as a predictor of DM comorbidity in active TB patients (aOR 5.11, 95% CI 2.01-12.98, p = 0.001).

conclusionThe magnitude of DM and pre-diabetes in active TB patients in Northwest Ethiopia was high, warranting collaborative efforts to improve screening and adopt better clinical management strategies for DM-TB comorbid patients. Furthermore, being rural residents, family history of DM and HIV/TB co-infection were found to associate with DM among TB patients, highlighting the importance of the above-mentioned risk factors in the clinical management of this comorbidity.

Indexed as

ComorbidityDiabetes mellitusNorthwest EthiopiaRisk factorsTuberculosis

Identifiers

PMID34454627
PMCPMC8403380

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.