SynthesisItalian journal of pediatrics2021
Italian consensus on the therapeutic management of uncomplicated acute hematogenous osteomyelitis in children.
Synthesis in Italian journal of pediatrics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed.
- Reflections on the Theoretical Prerequisites for Initial Oral Antibiotic Treatment for Paediatric Bone and Joint Infections: A Narrative Review.Antibiotics (Basel, Switzerland) · 2026Review
- Virtual Reality-Based Versus Traditional Teaching Approaches in the Oral Hygiene Education of Children with Autism Spectrum Disorder.Journal of clinical medicine · 2025Article
- Acute otomastoiditis in children: a scoping review on diagnosis and antibiotic regimens.European journal of pediatrics · 2025Article
- Neonatal osteomyelitis: a case series and literature review.Translational pediatrics · 2025Article
- Analysis of antimicrobial resistance and clinical features of Staphylococcus aureus-infected bone and joint infections in children.BMC pediatrics · 2025Article
- Duration of onset, body temperature and C-reactive protein can be used to predict the results of pus culture in children with acute osteomyelitis of long bones.Italian journal of pediatrics · 2024Article
- Appropriate Antibiotic Duration in Pediatric Bone and Joint Infection: A Systematic Review.Journal of the Pediatric Orthopaedic Society of North America · 2023Article
- Impact of a pediatric infectious disease consultation service on timely step-down to oral antibiotic treatment for bone and joint infections.Infection · 2023Article
- New insights in pediatrics in 2021: choices in allergy and immunology, critical care, endocrinology, gastroenterology, genetics, haematology, infectious diseases, neonatology, neurology, nutrition, palliative care, respiratory tract illnesses and telemedicine.Italian journal of pediatrics · 2022Review
- Risk Factors Affecting Development and Persistence of Preschool Wheezing: Consensus Document of the Emilia-Romagna Asthma (ERA) Study Group.Journal of clinical medicine · 2022Article
- Clinical report and predictors of sequelae of 319 cases of pediatric bacterial osteomyelitis.Scientific reports · 2022Article
- What Do We Know about Spondylodiscitis in Children? A Retrospective Study.Children (Basel, Switzerland) · 2022Article
- Surveillance of osteoarticular infections caused byFrontiers in cellular and infection microbiology · 2022Article
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44 authors.
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Abstract
backgroundAcute hematogenous osteomyelitis (AHOM) is an insidious infection of the bone that more frequently affects young males. The etiology, mainly bacterial, is often related to the patient's age, but it is frequently missed, owing to the low sensitivity of microbiological cultures. Thus, the evaluation of inflammatory biomarkers and imaging usually guide the diagnosis and follow-up of the infection. The antibiotic treatment of uncomplicated AHOM, on the other hand, heavily relies upon the clinician experience, given the current lack of national guidelines for the management of this infection.
methodsA systematic review of the studies on the empirical treatment of uncomplicated AHOM in children published in English or Italian between January 1, 2009, and March 31, 2020, indexed on Pubmed or Embase search engines, was carried out. All guidelines and studies reporting on non-bacterial or complicated or post-traumatic osteomyelitis affecting newborns or children older than 18 years or with comorbidities were excluded from the review. All other works were included in this study.
resultsOut of 4576 articles, 53 were included in the study. Data on different topics was gathered and outlined: bone penetration of antibiotics; choice of intravenous antibiotic therapy according to the isolated or suspected pathogen; choice of oral antibiotic therapy; length of treatment and switch to oral therapy; surgical treatment.
conclusionsThe therapeutic management of osteomyelitis is still object of controversy. This study reports the first Italian consensus on the management of uncomplicated AHOM in children of pediatric osteomyelitis, based on expert opinions and a vast literature review.
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