Evidence map›Paper›PMID 34454291›Full record

ReviewInternational immunopharmacology2021

Vaccine design and delivery approaches for COVID-19.

Kiana Shahzamani, Fatemeh Mahmoudian, Shahrzad Ahangarzadeh, Mohammad Mehdi Ranjbar, Leila Beikmohammadi, Samira Bahrami, Elmira Mohammadi, Sahar Esfandyari, Abbas Alibakhshi, Shaghayegh Haghjooy Javanmard

Abstract readReview
In one paragraph

Review in International immunopharmacology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Oral Lesions Following Anti-SARS-CoV-2 Vaccination: A Systematic Review.International journal of environmental research and public health · 2022
    Pooled it
  2. Review
  3. Review
  4. Review
  5. Article
  6. Article
  7. The economic case for scaling up health research and development: Lessons from the COVID-19 pandemic.Proceedings of the National Academy of Sciences of the United States of America · 2024
    Article
  8. Article
  9. Review
  10. Review
  11. Review
  12. From Immunogen to COVID-19 vaccines: Prospects for the post-pandemic era.Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie · 2023
    Review
  13. Article
  14. Efficacy and Safety of COVID-19 Vaccines-An Update.Diseases (Basel, Switzerland) · 2022
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Kiana ShahzamaniIsfahan Gastroenterology and Hepatology Research Center (lGHRC), Isfahan University of Medical Sciences, Isfahan, Iran.
Fatemeh MahmoudianDepartment of Molecular Medicine, School of Advanced Technologies in Medicine, Tehran University of Medical Sciences, Tehran, Iran.
Shahrzad AhangarzadehInfectious Diseases and Tropical Medicine Research Center, Isfahan University of Medical Sciences, Isfahan, Iran.
Mohammad Mehdi RanjbarRazi Vaccine and Serum Research Institute, Agricultural Research, Education, and Extension Organization (AREEO), Karaj, Iran.
Leila BeikmohammadiDepartment of Biochemistry, Erasmus University Medical Center, Rotterdam, the Netherlands; Stem Cell and Regenerative Medicine Center of Excellence, Tehran University of Medical Sciences, 14155-6559 Tehran, Iran.
Samira BahramiBiotechnology Department, School of Advanced Technologies in Medicine, Shahid Beheshti University of Medical Science, Tehran, Iran.
Elmira MohammadiApplied Physiology Research Center, Cardiovascular Research Institute, Department of Physiology, Isfahan University of Medical Sciences, Isfahan, Iran; Core Research Facilities, Isfahan University of Medical Sciences, Isfahan, Iran.
Sahar EsfandyariDepartment of Anatomy, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran.
Abbas AlibakhshiMolecular Medicine Research Center, Hamadan University of Medical Sciences, Hamadan, Iran. Electronic address: alibakhshi2630@yahoo.com.
Shaghayegh Haghjooy JavanmardApplied Physiology Research Center, Cardiovascular Research Institute, Department of Physiology, Isfahan University of Medical Sciences, Isfahan, Iran. Electronic address: sh_haghjoo@med.mui.ac.ir.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

COVID-19 is still a deadly disease that remains yet a major challenge for humans. In recent times, many large pharmaceutical and non-pharmaceutical companies have invested a lot of time and cost in fighting this disease. In this regard, today's scientific knowledge shows that designing and producing an effective vaccine is the best possible way to diminish the disease burden and dissemination or even eradicate the disease. Due to the urgent need, many vaccines are now available earlier than scheduled. New technologies have also helped to produce much more effective vaccines, although the potential side effects must be taken into account. Thus, in this review, the types of vaccines and vaccine designs made against COVID-19, the vaccination programs, as well as the delivery methods and molecules that have been used to deliver some vaccines that need a carrier will be described.

Indexed as

COVID-19COVID-19 VaccinesDrug ApprovalHealth Services AccessibilityHumansNanoparticlesSARS-CoV-2VaccinationCOVID-19 VaccinesCOVID-19SARS-CoV-2VaccineVaccine deliveryVaccine design

Identifiers

PMID34454291
PMCPMC8380485

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.