Evidence map›Paper›PMID 34453979›Full record

ArticleJournal of neuroscience methods2022

The Dome: A virtual reality apparatus for freely locomoting rodents.

Manu S Madhav, Ravikrishnan P Jayakumar, Shahin G Lashkari, Francesco Savelli, Hugh T Blair, James J Knierim, Noah J Cowan

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of neuroscience methods, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.3field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 20 citations in OpenAlex.

  1. Article
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  9. Article
  10. Review
  11. Article
  12. Wide-angle, monocular head tracking using passive markers.Journal of neuroscience methods · 2022
    Article
  13. Naturalistic neuroscience and virtual reality.Frontiers in systems neuroscience · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Manu S MadhavMind/Brain Institute, Johns Hopkins University, Baltimore, MD, USA; Kavli Neuroscience Discovery Institute, Johns Hopkins University, Baltimore, MD, USA; Laboratory for Computational Sensing and Robotics, Johns Hopkins University, Baltimore, MD, USA; School of Biomedical Engineering, Djawad Mowafaghian Centre for Brain Health, University of British Columbia, BC, Canada. Electronic address: manu.madhav@ubc.ca.
Ravikrishnan P JayakumarMind/Brain Institute, Johns Hopkins University, Baltimore, MD, USA; Laboratory for Computational Sensing and Robotics, Johns Hopkins University, Baltimore, MD, USA; Mechanical Engineering Department, Johns Hopkins University, Baltimore, MD, USA.
Shahin G LashkariLaboratory for Computational Sensing and Robotics, Johns Hopkins University, Baltimore, MD, USA; Mechanical Engineering Department, Johns Hopkins University, Baltimore, MD, USA.
Francesco SavelliMind/Brain Institute, Johns Hopkins University, Baltimore, MD, USA; Francesco Savelli is currently affiliated with the Department of Neuroscience, Developmental and Regenerative Biology, The University of Texas at San Antonio, San Antonio, TX, USA.
Hugh T BlairDepartment of Psychology, University of California Los Angeles, Los Angeles, CA, USA.
James J KnierimMind/Brain Institute, Johns Hopkins University, Baltimore, MD, USA; Kavli Neuroscience Discovery Institute, Johns Hopkins University, Baltimore, MD, USA.
Noah J CowanLaboratory for Computational Sensing and Robotics, Johns Hopkins University, Baltimore, MD, USA; Mechanical Engineering Department, Johns Hopkins University, Baltimore, MD, USA.
Johns Hopkins University · USDiscovery Institute · USUniversity of California, Los Angeles · US

Funding

A Control Theoretic Approach to Addressing Hippocampal FunctionR01NS102537 · NINDS · JOHNS HOPKINS UNIVERSITY · PI Noah John Cowan, JAMES J KNIERIM · 2017 to 2026
$3.6M
CRCNS: Path Intergration by the Grid Cell NetworkR01MH079511 · NIMH · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI BLAIR, HUGH T, KNIERIM, JAMES J · 2006 to 2015
$3.0M
A Control Theoretic Approach to Addressing Hippocampal FunctionR21NS095075 · NINDS · JOHNS HOPKINS UNIVERSITY · PI COWAN, NOAH JOHN · 2015 to 2016
$446k
NIMH NIH HHS R01 MH079511NINDS NIH HHS R01 NS102537NINDS NIH HHS R21 NS095075
6 · The paper itself

Abstract

The cognitive map in the hippocampal formation of rodents and other mammals integrates multiple classes of sensory and motor information into a coherent representation of space. Here, we describe the Dome, a virtual reality apparatus for freely locomoting rats, designed to examine the relative contributions of various spatial inputs to an animal's spatial representation. The Dome was designed to preserve the range of spatial inputs typically available to an animal in free, untethered locomotion while providing the ability to perturb specific sensory cues. We present the design rationale and corresponding specifications of the Dome, along with a variety of engineering and biological analyses to validate the efficacy of the Dome as an experimental tool to examine the interaction between visual information and path integration in place cells in rodents.

Indexed as

Space PerceptionVirtual RealityAnimalsCuesHippocampusRatsRodentiaCognitive mapControl theoryMultisensory integrationVirtual reality

Identifiers

PMID34453979
PMCPMC9178503
OpenAlexW3197296566

What OpenQuestion holds

Textmetadata
LicenceCC BY-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.