Evidence map›Paper›PMID 34453948›Full record

ArticleLife sciences2021

Boston biorepository, recruitment and integrative network (BBRAIN): A resource for the Gulf War Illness scientific community.

D Keating, C G Zundel, M Abreu, M Krengel, K Aenlle, M D Nichols, R Toomey, L L Chao, J Golier, L Abdullah and 19 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Life sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

29 authors.

D KeatingBoston University School of Public Health, Department of Environmental Health, 715 Albany St. T4W, Boston, MA 02118, USA. Electronic address: dmk13@bu.edu.
C G ZundelBoston University School of Medicine, Behavioral Neuroscience Program, 72 East Concord St., Boston, MA 02118, USA. Electronic address: cgzundel@bu.edu.
M AbreuDr. Kiran C. Patel College of Osteopathic Medicine, Institute for Neuroimmune Medicine, Nova Southeastern University, Fort Lauderdale, FL 33314, USA; Geriatric Research Education and Clinical Center, Miami VA Medical Center, Miami, FL 33125, USA. Electronic address: mabreu1@nova.edu.
M KrengelBoston University School of Medicine, Department of Neurology, 72 East Concord St., Boston, MA 02118, USA. Electronic address: mhk@bu.edu.
K AenlleDr. Kiran C. Patel College of Osteopathic Medicine, Institute for Neuroimmune Medicine, Nova Southeastern University, Fort Lauderdale, FL 33314, USA; Geriatric Research Education and Clinical Center, Miami VA Medical Center, Miami, FL 33125, USA. Electronic address: kaenlle@nova.edu.
M D NicholsBoston University School of Public Health, Department of Environmental Health, 715 Albany St. T4W, Boston, MA 02118, USA.
R ToomeyDepartment of Psychological and Brain Sciences, College of Arts and Sciences, Boston University, 900 Commonwealth Ave., Boston, MA, USA. Electronic address: toomey@bu.edu.
L L ChaoSan Francisco Veterans Affairs Health Care System, University of California, San Francisco, CA 94143, USA. Electronic address: linda.chao@ucsf.edu.
J GolierJames J. Peters VA Medical Center, OOMH-526, 130 West Kingsbridge Road, Bronx, NY 10468, USA; Psychiatry Department, Icahn School of Medicine at Mount Sinai, 1428 Madison Ave, New York, NY 10029, USA. Electronic address: julia.golier@va.gov.
L AbdullahRoskamp Institute, 2040 Whitfield Ave, Sarasota, FL 34243, USA; Open University, Milton Keynes, United Kingdom; James A. Haley Veterans' Hospital, Tampa, FL, USA. Electronic address: labdullah@roskampinstitute.org.
E QuinnBoston University School of Public Health, Department of Biostatistics, 715 Albany St., Boston, MA 02118, USA. Electronic address: eq@bu.edu.
T HeerenBoston University School of Public Health, Department of Biostatistics, 715 Albany St., Boston, MA 02118, USA. Electronic address: tch@bu.edu.
J R GrohBoston University School of Medicine, Behavioral Neuroscience Program, 72 East Concord St., Boston, MA 02118, USA. Electronic address: jengroh@bu.edu.
B B KooBoston University School of Medicine, Department of Anatomy and Neurobiology, 72 East Concord St., Boston, MA 02118, USA. Electronic address: bbkoo@bu.edu.
R KillianyBoston University School of Public Health, Department of Environmental Health, 715 Albany St. T4W, Boston, MA 02118, USA; Boston University School of Medicine, Department of Neurology, 72 East Concord St., Boston, MA 02118, USA; Boston University School of Medicine, Department of Anatomy and Neurobiology, 72 East Concord St., Boston, MA 02118, USA. Electronic address: killiany@bu.edu.
M L LoggiaDepartment of Radiology, Athinoula A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Harvard Medical School, Charlestown, MA, USA. Electronic address: marco.loggia@mgh.harvard.edu.
J YoungerNeuroinflammation, Pain & Fatigue Lab, University of Alabama at Birmingham, Birmingham, AL, USA. Electronic address: younger@uab.edu.
J BaraniukDepartment of Medicine, Georgetown University, Washington, DC, USA. Electronic address: baraniuj@georgetown.edu.
P JanulewiczBoston University School of Public Health, Department of Environmental Health, 715 Albany St. T4W, Boston, MA 02118, USA. Electronic address: paj@bu.edu.
J AjamaBoston University School of Public Health, Department of Environmental Health, 715 Albany St. T4W, Boston, MA 02118, USA. Electronic address: ajamaj@bu.edu.
M QuayBoston University School of Public Health, Department of Environmental Health, 715 Albany St. T4W, Boston, MA 02118, USA. Electronic address: quaym@bu.edu.
P W BaasDrexel University College of Medicine, Department of Neurobiology and Anatomy, 2900 Queen Lane, Philadelphia, PA 19129, USA. Electronic address: pwb22@drexel.edu.
L QiangDrexel University College of Medicine, Department of Neurobiology and Anatomy, 2900 Queen Lane, Philadelphia, PA 19129, USA. Electronic address: lq24@drexel.edu.
L ConboyDepartment of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02115, USA. Electronic address: lisa_conboy@hms.haravard.edu.
E KokkotouDepartment of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02115, USA. Electronic address: ekokkoto@bidmc.harvard.edu.
J P O'CallaghanHealth Effects Laboratory Division, Centers for Disease Control and Prevention, National Institute for Occupational Safety and Health, Morgantown, WV, USA. Electronic address: jdo5@cdc.gov.
L SteeleBaylor College of Medicine Neuropsychiatry Division, Department of Psychiatry and Behavioral Sciences, Houston, TX 77030, USA. Electronic address: Lea.Steele@bcm.edu.
N KlimasDr. Kiran C. Patel College of Osteopathic Medicine, Institute for Neuroimmune Medicine, Nova Southeastern University, Fort Lauderdale, FL 33314, USA; Geriatric Research Education and Clinical Center, Miami VA Medical Center, Miami, FL 33125, USA. Electronic address: nklimas@bu.edu.
K SullivanBoston University School of Public Health, Department of Environmental Health, 715 Albany St. T4W, Boston, MA 02118, USA. Electronic address: tty@bu.edu.

Funding

Elucidating the etiology of SPAST-based Hereditary Spastic ParaplegiaR01NS115977 · NINDS · DREXEL UNIVERSITY · PI QIANG, LIANG · 2021 to 2025
$1.8M
NINDS NIH HHS R01 NS115977
6 · The paper itself

Abstract

aimsGulf War Illness (GWI), a chronic debilitating disorder characterized by fatigue, joint pain, cognitive, gastrointestinal, respiratory, and skin problems, is currently diagnosed by self-reported symptoms. The Boston Biorepository, Recruitment, and Integrative Network (BBRAIN) is the collaborative effort of expert Gulf War Illness (GWI) researchers who are creating objective diagnostic and pathobiological markers and recommend common data elements for GWI research. MAIN

methodsBBRAIN is recruiting 300 GWI cases and 200 GW veteran controls for the prospective study. Key data and biological samples from prior GWI studies are being merged and combined into retrospective datasets. They will be made available for data mining by the BBRAIN network and the GWI research community. Prospective questionnaire data include general health and chronic symptoms, demographics, measures of pain, fatigue, medical conditions, deployment and exposure histories. Available repository biospecimens include blood, plasma, serum, saliva, stool, urine, human induced pluripotent stem cells and cerebrospinal fluid. KEY

findingsTo date, multiple datasets have been merged and combined from 15 participating study sites. These data and samples have been collated and an online request form for repository requests as well as recommended common data elements have been created. Data and biospecimen sample requests are reviewed by the BBRAIN steering committee members for approval as they are received. SIGNIFICANCE: The BBRAIN repository network serves as a much needed resource for GWI researchers to utilize for identification and validation of objective diagnostic and pathobiological markers of the illness.

Indexed as

BostonHumansInformation DisseminationMagnetic Resonance ImagingPersian Gulf SyndromePositron-Emission TomographySalivaBBRAINGulf warGulf war illnessGWIGWIC

Identifiers

PMID34453948
PMCPMC9643044

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.