Evidence map›Paper›PMID 34453876›Full record

ArticleJournal of applied clinical medical physics2021

A novel angular dependency model for MatriXX response and its application to true composite dose verification for IMRT plans.

Yin Zhou, Jiugao Sang, Haibo Chen, Meng Zhu, He Wang, Shuwei Zhai, Lina Lu, Hui Liu, Zhengfei Zhu, Zhouguang Hui and 2 more

Abstract read
In one paragraph

Article in Journal of applied clinical medical physics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

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0cells of the map it votes in
2citing papers in PubMed
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1 · What the graph read from it

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

12 authors.

Yin ZhouEvidance Medical Technologies Inc., Suzhou, China.
Jiugao SangDepartment of Radiation Oncology, Rudong County People's Hospital, Rudong, China.
Haibo ChenDepartment of Radiation Oncology, The Affiliated Suzhou Science and Technology Town Hospital of Nanjing Medical University, Suzhou, China.
Meng ZhuEvidance Medical Technologies Inc., Suzhou, China.ORCID https://orcid.org/0000-0002-8521-5072
He WangHomology Medical Technologies Inc., Ningbo, China.
Shuwei ZhaiDepartment of Radiation Oncology, The Affiliated Suzhou Science and Technology Town Hospital of Nanjing Medical University, Suzhou, China.
Lina LuDepartment of Radiation Oncology, The Affiliated Suzhou Science and Technology Town Hospital of Nanjing Medical University, Suzhou, China.
Hui LiuDepartment of Radiation Oncology, State Key Laboratory of Oncology in South China, Sun Yat-sen University Cancer Center, Guangzhou, China.
Zhengfei ZhuDepartment of Radiation Oncology, Fudan University Shanghai Cancer Center, Shanghai, China.
Zhouguang HuiDepartment of Radiation Oncology, National Cancer Center/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
Jianrong DaiDepartment of Radiation Oncology, National Cancer Center/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
Jian HuanDepartment of Radiation Oncology, The Affiliated Suzhou Science and Technology Town Hospital of Nanjing Medical University, Suzhou, China.

Funding

National Key R&D Program of China 2018YFC0116800National Natural Science Foundation of China 11875320Suzhou Municipal Science and Technology Program SYS2018009Suzhou New and High-Tech Zone Healthcare Program 2017Z001
6 · The paper itself

Abstract

purposeThis paper proposes a model for the angular dependency of MatriXX response and investigates whether MatriXX, with the angular-model-based approach can be applied to true composite dose verification for IMRT plans.

methodThis model attributes the angular dependence of MatriXX response to dynamical translation of its effective measurement plane (EMP) due to the change of beam angle. Considering this mechanism, true composite dose verifications for IMRT plans specified in AAPM TG 119 report using both MatriXX and Gafchromic EBT3 films were undertook and compared to validate the applicability of MatriXX for patient specific QA of composite beam IMRT plans. Dose verifications using MatriXX with and without angular-model-based approach were performed.

resultsMatriXX with angular-model-based approach achieved gamma passing rates with 3%/3 mm and 3%/2 mm criteria better than 98.3% and 98.1% respectively for true composite dose verification of plans in AAPM TG 119 report. The 3%/3 mm and 3%/2 mm gamma passing rates using MatriXX without angular-model-based approach ranged from 85.8% to 98.2% and from 81.3% to 96.5%, respectively. The p-values from the single sided paired t-test indicated no statistical difference between the passing rates from MatriXX with angular-model-based approach and from films, and significant difference between the passing rates from uncorrected MatriXX and from films.

conclusionThe proposed model for angular dependent MatriXX response is necessary and effective. Dose verification using MatriXX with angular-model-based approach is acceptable for true composite beam IMRT plans with required accuracy to simplify patient specific QA.

Indexed as

Radiotherapy, Intensity-ModulatedGamma RaysHumansRadiometryRadiotherapy DosageRadiotherapy Planning, Computer-Assistedangular responseIMRTMatriXXmechanism of angular dependencypatient specific QAradiotherapytrue composite dose verification

Identifiers

PMID34453876
PMCPMC8504602

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