Evidence map›Paper›PMID 34453696›Full record

ArticleBiomolecular NMR assignments2021

Christian Richter, Katharina F Hohmann, Sabrina Toews, Daniel Mathieu, Nadide Altincekic, Jasleen Kaur Bains, Oliver Binas, Betül Ceylan, Elke Duchardt-Ferner, Jan Ferner and 23 more

Open access · hybridAbstract read
In one paragraph

Article in Biomolecular NMR assignments, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.5field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
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  3. Biomolecular NMR assignments · 2025
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  6. NMRRSC medicinal chemistry · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

33 authors at 3 institutions in 2 countries.

Christian Richter *Institute for Organic Chemistry and Chemical Biology, Goethe-University Frankfurt, Max-von-Laue- Straße 7, 60438, Frankfurt, Germany.
Katharina F Hohmann *Institute for Organic Chemistry and Chemical Biology, Goethe-University Frankfurt, Max-von-Laue- Straße 7, 60438, Frankfurt, Germany.
Sabrina ToewsInstitute for Organic Chemistry and Chemical Biology, Goethe-University Frankfurt, Max-von-Laue- Straße 7, 60438, Frankfurt, Germany.
Daniel MathieuBruker BioSpin, Silberstreifen 4, 76287, Rheinstetten, Germany.
Nadide AltincekicInstitute for Organic Chemistry and Chemical Biology, Goethe-University Frankfurt, Max-von-Laue- Straße 7, 60438, Frankfurt, Germany.
Jasleen Kaur BainsInstitute for Organic Chemistry and Chemical Biology, Goethe-University Frankfurt, Max-von-Laue- Straße 7, 60438, Frankfurt, Germany.
Oliver BinasInstitute for Organic Chemistry and Chemical Biology, Goethe-University Frankfurt, Max-von-Laue- Straße 7, 60438, Frankfurt, Germany.
Betül CeylanInstitute for Organic Chemistry and Chemical Biology, Goethe-University Frankfurt, Max-von-Laue- Straße 7, 60438, Frankfurt, Germany.
Elke Duchardt-FernerCenter for Biomolecular Magnetic Resonance (BMRZ), Goethe-University Frankfurt, Max-von-Laue- Straße 7, 60438, Frankfurt, Germany.
Jan FernerInstitute for Organic Chemistry and Chemical Biology, Goethe-University Frankfurt, Max-von-Laue- Straße 7, 60438, Frankfurt, Germany.
Boris FürtigInstitute for Organic Chemistry and Chemical Biology, Goethe-University Frankfurt, Max-von-Laue- Straße 7, 60438, Frankfurt, Germany.
J Tassilo GrünInstitute for Organic Chemistry and Chemical Biology, Goethe-University Frankfurt, Max-von-Laue- Straße 7, 60438, Frankfurt, Germany.
Martin HengesbachInstitute for Organic Chemistry and Chemical Biology, Goethe-University Frankfurt, Max-von-Laue- Straße 7, 60438, Frankfurt, Germany.
Daniel HymonInstitute for Organic Chemistry and Chemical Biology, Goethe-University Frankfurt, Max-von-Laue- Straße 7, 60438, Frankfurt, Germany.
Hendrik R A JonkerInstitute for Organic Chemistry and Chemical Biology, Goethe-University Frankfurt, Max-von-Laue- Straße 7, 60438, Frankfurt, Germany.
Bozana KnezicInstitute for Organic Chemistry and Chemical Biology, Goethe-University Frankfurt, Max-von-Laue- Straße 7, 60438, Frankfurt, Germany.
Sophie M KornCenter for Biomolecular Magnetic Resonance (BMRZ), Goethe-University Frankfurt, Max-von-Laue- Straße 7, 60438, Frankfurt, Germany.
Tom LandgrafInstitute for Organic Chemistry and Chemical Biology, Goethe-University Frankfurt, Max-von-Laue- Straße 7, 60438, Frankfurt, Germany.
Frank LöhrCenter for Biomolecular Magnetic Resonance (BMRZ), Goethe-University Frankfurt, Max-von-Laue- Straße 7, 60438, Frankfurt, Germany.
Stephen A PeterDepartment of Biology, Technical University of Darmstadt, Schnittspahnstraße 10, 64287, Darmstadt, Germany.
Dennis J PyperInstitute for Organic Chemistry and Chemical Biology, Goethe-University Frankfurt, Max-von-Laue- Straße 7, 60438, Frankfurt, Germany.
Nusrat S QureshiInstitute for Organic Chemistry and Chemical Biology, Goethe-University Frankfurt, Max-von-Laue- Straße 7, 60438, Frankfurt, Germany.
Andreas SchlundtCenter for Biomolecular Magnetic Resonance (BMRZ), Goethe-University Frankfurt, Max-von-Laue- Straße 7, 60438, Frankfurt, Germany.
Robbin SchniedersInstitute for Organic Chemistry and Chemical Biology, Goethe-University Frankfurt, Max-von-Laue- Straße 7, 60438, Frankfurt, Germany.
Elke StirnalInstitute for Organic Chemistry and Chemical Biology, Goethe-University Frankfurt, Max-von-Laue- Straße 7, 60438, Frankfurt, Germany.
Alexey SudakovInstitute for Organic Chemistry and Chemical Biology, Goethe-University Frankfurt, Max-von-Laue- Straße 7, 60438, Frankfurt, Germany.
Jennifer VögeleCenter for Biomolecular Magnetic Resonance (BMRZ), Goethe-University Frankfurt, Max-von-Laue- Straße 7, 60438, Frankfurt, Germany.
Julia E WeigandDepartment of Biology, Technical University of Darmstadt, Schnittspahnstraße 10, 64287, Darmstadt, Germany.
Julia Wirmer-BartoschekInstitute for Organic Chemistry and Chemical Biology, Goethe-University Frankfurt, Max-von-Laue- Straße 7, 60438, Frankfurt, Germany.
Kerstin WittInstitute for Organic Chemistry and Chemical Biology, Goethe-University Frankfurt, Max-von-Laue- Straße 7, 60438, Frankfurt, Germany.
Jens WöhnertCenter for Biomolecular Magnetic Resonance (BMRZ), Goethe-University Frankfurt, Max-von-Laue- Straße 7, 60438, Frankfurt, Germany.
Harald SchwalbeInstitute for Organic Chemistry and Chemical Biology, Goethe-University Frankfurt, Max-von-Laue- Straße 7, 60438, Frankfurt, Germany. schwalbe@nmr.uni-frankfurt.de.ORCID 0000-0001-5693-7909
Anna WackerInstitute for Organic Chemistry and Chemical Biology, Goethe-University Frankfurt, Max-von-Laue- Straße 7, 60438, Frankfurt, Germany. wacker@nmr.uni-frankfurt.de.
Goethe University Frankfurt · DETechnische Universität Darmstadt · DEBruker (Germany) · DE

Funding

deutsche forschungsgemeinschaft 277478796deutsche forschungsgemeinschaft 277479031deutsche forschungsgemeinschaft 392682309deutsche forschungsgemeinschaft 452632086deutsche forschungsgemeinschaft 70653611deutsche forschungsgemeinschaft CLICdeutsche forschungsgemeinschaft CRC 902deutsche forschungsgemeinschaft FOR2509deutsche forschungsgemeinschaft SPP1879deutsche forschungsgemeinschaft SPP2002deutsche forschungsgemeinschaft TRR 267goethe-universität frankfurt am main Goethe Corona Fondshessisches ministerium für wissenschaft und kunst BMRZhessisches ministerium für wissenschaft und kunst IWB-EFRE-programme 20007375
6 · The paper itself

Abstract

The stem-loop (SL1) is the 5'-terminal structural element within the single-stranded SARS-CoV-2 RNA genome. It is formed by nucleotides 7-33 and consists of two short helical segments interrupted by an asymmetric internal loop. This architecture is conserved among Betacoronaviruses. SL1 is present in genomic SARS-CoV-2 RNA as well as in all subgenomic mRNA species produced by the virus during replication, thus representing a ubiquitous cis-regulatory RNA with potential functions at all stages of the viral life cycle. We present here the

Indexed as

5' Untranslated RegionsNitrogen IsotopesRNA, ViralSARS-CoV-2Base SequenceCarbon IsotopesNuclear Magnetic Resonance, BiomolecularNucleic Acid Conformation5' Untranslated RegionsCarbon-13Carbon IsotopesNitrogen-15Nitrogen IsotopesRNA, Viral5'-UTRCOVID19-NMRSARS-CoV-2SL1Solution NMR spectroscopy

Identifiers

PMID34453696
PMCPMC8401371
OpenAlexW3194401170

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.