Evidence map›Paper›PMID 34453684›Full record

ArticleJournal of cancer survivorship : research and practice2022

Sensory signs and symptoms in women with self-reported breast cancer-related lymphedema: a case-control study close up.

An De Groef, Nele Devoogdt, Ceren Gursen, Niamh Moloney, Victoria Warpy, Jolien Daelemans, Lore Dams, Vincent Haenen, Elien Van der Gucht, An-Kathleen Heroes and 2 more

Erratum issuedOpen access · greenAbstract read
PubMed Publisher
In one paragraph

Article in Journal of cancer survivorship : research and practice, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
0.7field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it, 14 citations in OpenAlex.

  1. Evidence for the clinical effectiveness of decongestive lymphoedema treatment for breast cancer-related arm lymphoedema, a systematic review.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2024
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

12 authors at 5 institutions in 4 countries.

An De GroefDepartment of Rehabilitation Sciences, KU Leuven - University of Leuven, Leuven, Belgium. an.degroef@kuleuven.be.ORCID 0000-0001-6771-2836
Nele DevoogdtDepartment of Rehabilitation Sciences, KU Leuven - University of Leuven, Leuven, Belgium.ORCID 0000-0002-8117-7080
Ceren GursenFaculty of Physical Therapy and Rehabilitation, Hacettepe University, Ankara, Turkey.ORCID 0000-0002-9204-8364
Niamh MoloneyDepartment of Health Professions, Faculty of Medicine, Health and Human Sciences, Macquarie University, Sydney, NSW, Australia.ORCID 0000-0001-5957-7224
Victoria WarpyDepartment of Rehabilitation Sciences, KU Leuven - University of Leuven, Leuven, Belgium.
Jolien DaelemansDepartment of Rehabilitation Sciences, KU Leuven - University of Leuven, Leuven, Belgium.
Lore DamsDepartment of Rehabilitation Sciences, KU Leuven - University of Leuven, Leuven, Belgium.ORCID 0000-0002-1283-6185
Vincent HaenenDepartment of Rehabilitation Sciences, KU Leuven - University of Leuven, Leuven, Belgium.ORCID 0000-0001-7056-6286
Elien Van der GuchtDepartment of Rehabilitation Sciences, KU Leuven - University of Leuven, Leuven, Belgium.ORCID 0000-0002-9778-1143
An-Kathleen HeroesDepartment of Rehabilitation Sciences, KU Leuven - University of Leuven, Leuven, Belgium.
Tessa De VriezeDepartment of Rehabilitation Sciences, KU Leuven - University of Leuven, Leuven, Belgium.ORCID 0000-0002-5719-6169
Elizabeth DylkeFaculty of Medicine and Health, The University of Sydney, Lidcombe, NSW, Australia.ORCID 0000-0002-7115-8142
University of Antwerp · BEKU Leuven · BECalifornia State University, Channel Islands · USHacettepe University · TRThe University of Sydney · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeIt is not clear to what extent signs and symptoms other than arm swelling, including pain, altered sensory function, and body perception disturbances, differ between women with measurable and non-measurable breast cancer-related lymphedema (BCRL). A case-control study was performed to compare these signs and symptoms between (1) women with self-reported BCRL with objectively measurable swelling; (2) women with self-reported BCRL without objective confirmation; and (3) a control group with no self-reported BCRL.

methodsThe three groups were compared for (1) the severity of self-reported signs and symptoms of BCRL, (2) problems in functioning related to BCRL, (3) pain-related outcomes, (4) sensory functions, and (5) body perception.

resultsAll self-reported outcomes related to signs and symptoms of BCRL and problems in functioning were significantly different between the control group and the other two groups with and without measurable self-reported BCRL (p < 0.001-0.003). Except for "skin texture" (p = 0.01), "hand swelling" (p=0.301) and 'difficulty writing' (p=0.676), no differences were found between groups. For pain-related outcomes, sensory function, and body perception, significant differences were only found for the mechanical detection threshold (p < 0.01) and self-reported disturbances in body perception (p < 0.001) between the self-reported BCRL groups and control group.

conclusionsDiverse signs and symptoms related to BCRL, sensory function, and perception were different among women with self-reported BCRL compared to controls. No differences between women with and without measurable self-reported BCRL were found. IMPLICATIONS FOR CANCER SURVIVORS: The presence of self-reported BCRL, with or without measurable swelling, is a first indication for the need of further diagnostic evaluation.

Indexed as

Breast NeoplasmsLymphedemaCase-Control StudiesFemaleHumansPainSelf ReportBody perceptionBreast neoplasmsLymphedemaPainSensory functionSigns and symptoms

Identifiers

PMID34453684
OpenAlexW3194373222

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.