Evidence map›Paper›PMID 34453674›Full record

ArticleMolecular biology reports2021

Cloning of Mn-SOD gene and its mRNA expression difference and antioxidant enzyme activities under hypoxia stress of cobia Rachycentron canadum.

Jian-Dong Zhang, Hong-Juan Li, Eric Amenyogbe, Wei-Zheng Wang, Jian-Sheng Huang, Gang Chen

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Article in Molecular biology reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.6field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 9 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Jian-Dong Zhang *Fishery College, Guangdong Ocean University, Zhanjiang, 524025, China.
Hong-Juan Li *Fishery College, Guangdong Ocean University, Zhanjiang, 524025, China.
Eric AmenyogbeFishery College, Guangdong Ocean University, Zhanjiang, 524025, China.
Wei-Zheng WangFishery College, Guangdong Ocean University, Zhanjiang, 524025, China.
Jian-Sheng HuangFishery College, Guangdong Ocean University, Zhanjiang, 524025, China. huangjs@gdou.edu.cn.
Gang ChenFishery College, Guangdong Ocean University, Zhanjiang, 524025, China. cheng@gdou.edu.cn.
Guangdong Ocean University · CN

Funding

Agriculture Research System of China CARS-47Guangdong Ocean University Undergraduate Innovation and Entrepreneurship Training Programs CXXL2018131Southern Marine Science and Engineering Guangdong Laboratory (Zhanjiang) ZJW-2019-06
6 · The paper itself

Abstract

backgroundEnvironmental hypoxia affects the survival and development of organisms. It is also an important environmental factor that leads to oxidative damage. Hypoxia is a condition in which tissues are deprived of oxygen; reoxygenation is the phenomenon in which hypoxic tissues are exposed to oxygen. Hypoxia-reoxygenation is vital in pathogenesis, where the production of reactive oxygen species and antioxidant disparity significantly contribute to disease progression, and it is one of the most common physiological stressors in the aquaculture industry. METHODS AND

resultsIn this study, the full length of complementary DNA (cDNA) of the manganese superoxide dismutase (Mn-SOD) gene of healthy cobia Rachycentron canadum was analysed using rapid amplification of cDNA ends. The real-time quantitative Polymerase Chain Reaction was used to measure the expression levels of Mn-SOD mRNAs in various tissues (heart, muscle, brain, liver, kidney, gill, intestine, and spleen). The 2

conclusionsThese results provide valuable information on the role of Mn-SOD regulation in oxidative stress caused by hypoxia.

Indexed as

Gene Expression Regulation, EnzymologicStress, PhysiologicalAmino Acid SequenceAnimalsAntioxidantsBase SequenceCell HypoxiaCloning, MolecularDNA, ComplementaryGene Expression ProfilingModels, MolecularOxidative StressPerciformesPhylogenyRNA, MessengerSuperoxide DismutaseAntioxidantsDNA, ComplementaryRNA, MessengerSuperoxide DismutaseGene cloningHypoxia stressMn-SOD genemRNA expressionRachycentron canadum

Identifiers

PMID34453674
OpenAlexW3196147768

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.