Evidence map›Paper›PMID 34453644›Full record

ReviewMolecular and cellular biochemistry2021

Vitamin D deficiency: concern for rheumatoid arthritis and COVID-19?

Sneha Verma, Ved Chaturvedi, N K Ganguly, Shivani Arora Mittal

Open access · bronzeAbstract readReview
In one paragraph

Review in Molecular and cellular biochemistry, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
17.5field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 86 citations in OpenAlex.

  1. The Role of Vitamin D in Autoimmune Diseases.International journal of molecular sciences · 2026
    Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Sneha VermaDepartment of Research, Sir Ganga Ram Hospital, New Delhi, India.
Ved ChaturvediDepartment of Rheumatology & Clinical Immunology, Sir Ganga Ram Hospital, New Delhi, India.
N K GangulyDepartment of Research, Sir Ganga Ram Hospital, New Delhi, India.
Shivani Arora MittalDepartment of Research, Sir Ganga Ram Hospital, New Delhi, India. shivanimittal@icloud.com.ORCID http://orcid.org/0000-0001-9734-3488
Sir Ganga Ram Hospital · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Vitamin D is an immunomodulatory hormone with an established role in calcium and phosphate metabolism and skeletal mineralization. Evidence showing its immunological benefits by regulating essential components of the innate and adaptive immune system is prevalent. Vitamin D deficiency is reported worldwide and is thereby found to be associated with various immune-related diseases. Rheumatoid Arthritis and COVID-19 are two such diseases, sharing a similar hyperinflammatory response. Various studies have found an association of lower Vitamin D levels to be associated with both these diseases. However, contrasting data is also reported. We review here the available scientific data on risk factor association and supplementation benefits of Vitamin D in Rheumatoid Arthritis and COVID-19, intending to critically evaluate the literature.

Indexed as

Arthritis, RheumatoidCOVID-19HumansRisk FactorsVitamin DVitamin D DeficiencyVitamin DAssociationCOVID-19DeficiencyRheumatoid arthritisSupplementationVitamin D

Identifiers

PMID34453644
PMCPMC8401347
OpenAlexW3194341628

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.