Evidence map›Paper›PMID 34453600›Full record

ReviewPediatric nephrology (Berlin, Germany)2022

Kidney implications of SARS-CoV2 infection in children.

Erica C Bjornstad, Michael E Seifert, Keia Sanderson, Daniel I Feig

Open access · bronzeAbstract readReview
In one paragraph

Review in Pediatric nephrology (Berlin, Germany), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.0field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 16 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Acute kidney injury: a post-COVID-19 complication in children and adolescents.Revista paulista de pediatria : orgao oficial da Sociedade de Pediatria de Sao Paulo · 2024
    Article
  5. Article
  6. Article
  7. Review
  8. Article
  9. Article
  10. [Long-term physical and psychological consequences of chronic kidney disease].Bundesgesundheitsblatt, Gesundheitsforschung, Gesundheitsschutz · 2022
    Review
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Erica C BjornstadDepartment of Pediatrics, Nephrology, University of Alabama at Birmingham, Birmingham, AL, USA. ebjornstad@uabmc.edu.ORCID http://orcid.org/0000-0002-4191-9510
Michael E SeifertDepartment of Pediatrics, Nephrology, University of Alabama at Birmingham, Birmingham, AL, USA.
Keia SandersonDepartment of Medicine, Nephrology and Hypertension, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
Daniel I FeigDepartment of Pediatrics, Nephrology, University of Alabama at Birmingham, Birmingham, AL, USA.
University of Alabama at Birmingham · USUniversity of Alabama at Birmingham Hospital · USUniversity of North Carolina at Chapel Hill · US

Funding

Clinical and Molecular Biomarkers of Endpoints in Pediatric Renal TransplantationR01DK126807 · NIDDK · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI SEIFERT, MICHAEL EDWARD · 2020 to 2024
$1.5M
NIDDK NIH HHS R01 DK126807
6 · The paper itself

Abstract

Research indicates that severe acute respiratory syndrome coronavirus 2 (SARS-CoV2) infection can impact every organ, and the effects can range from asymptomatic to severe disease. Since it was first discovered in December 2019, our understanding has grown about its impact on kidney disease. In general, children have less severe disease than adults, and this tendency appears to extend to special pediatric kidney populations (e.g., chronic kidney disease and immunosuppressed patients with solid organ transplants or nephrotic syndrome). However, in a fraction of infected children, SARS-CoV2 causes an array of kidney manifestations, ranging from acute kidney injury to thrombotic microangiopathy, with potential implications for increased risk of morbidity and mortality. Additional considerations surround the propensity for clotting extracorporeal circuits in children with SARS-CoV2 infection that are receiving kidney replacement therapy. This review provides an update on our current understanding of SARS-CoV2 for pediatric nephrologists and highlights knowledge gaps to be addressed by future research during this ongoing pandemic, particularly the social disparities magnified during this period.

Indexed as

Acute Kidney InjuryCOVID-19AdultChildHumansKidneyRNA, ViralSARS-CoV-2RNA, ViralAcute kidney injuryChronic kidney diseaseCOVID-19DialysisEpidemiologyGlomerular diseasesPediatric nephrologySARS-CoV2Transplant

Identifiers

PMID34453600
PMCPMC8397606
OpenAlexW3196072567

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.