Evidence map›Paper›PMID 34453574›Full record

ArticleEuropean radiology2022

Improving the accuracy of prognosis for clinical stage I solid lung adenocarcinoma by radiomics models covering tumor per se and peritumoral changes on CT.

Kunfeng Liu, Kunwei Li, Tingfan Wu, Mingzhu Liang, Yinghua Zhong, Xiangyang Yu, Xin Li, Chuanmiao Xie, Lanjun Zhang, Xueguo Liu

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In one paragraph

Article in European radiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed, 1 pooled it
4.6field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

32 citing papers in PubMed, 1 synthesis or guideline pooled it, 47 citations in OpenAlex.

  1. Pooled it
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  8. Intratumoral and peritumoral radiomics model for the preoperative prediction of cribriform component in invasive lung adenocarcinoma: a multicenter study.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2025
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  17. CT-based conventional radiomics and quantification of intratumoral heterogeneity for predicting benign and malignant renal lesions.Cancer imaging : the official publication of the International Cancer Imaging Society · 2024
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  19. [Prediction of recurrence-free survival in lung adenocarcinoma based on self-supervised pre-training and multi-task learning].Sheng wu yi xue gong cheng xue za zhi = Journal of biomedical engineering = Shengwu yixue gongchengxue zazhi · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 1 country.

Kunfeng Liu *Department of Radiology, Fifth Affiliated Hospital of Sun Yat-sen University, Zhuhai, China.
Kunwei Li *Department of Radiology, Fifth Affiliated Hospital of Sun Yat-sen University, Zhuhai, China.
Tingfan WuTranslational Medicine Team, GE Healthcare, Shanghai, China.
Mingzhu LiangDepartment of Radiology, Fifth Affiliated Hospital of Sun Yat-sen University, Zhuhai, China.
Yinghua ZhongDepartment of Radiology, Fifth Affiliated Hospital of Sun Yat-sen University, Zhuhai, China.
Xiangyang YuState Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Department of Thoracic Surgery, Sun Yat-sen University Cancer Center, Guangzhou, China.
Xin LiTranslational Medicine Team, GE Healthcare, Shanghai, China.
Chuanmiao XieDepartment of Radiology, Sun Yat-sen University Cancer Center, Guangzhou, China.
Lanjun ZhangDepartment of Thoracic Surgery, Sun Yat-sen University Cancer Center, Guangzhou, China.
Xueguo LiuDepartment of Radiology, Fifth Affiliated Hospital of Sun Yat-sen University, Zhuhai, China. liuxueg@mail.sysu.edu.cn.
Sun Yat-sen University · CNSun Yat-sen University Cancer Center · CNUnited Imaging Healthcare (China) · CNThe Seventh Affiliated Hospital of Sun Yat-sen University · CN

Funding

Guangdong Ministry of Education Industry-University-Research Project 2011A090200057
6 · The paper itself

Abstract

objectivesTo assess methods to improve the accuracy of prognosis for clinical stage I solid lung adenocarcinoma using radiomics based on different volumes of interests (VOIs).

methodsThis retrospective study included patients with postoperative clinical stage I solid lung adenocarcinoma from two hospitals, center 1 and center 2. Three databases were generated: dataset A (training set from center 1), dataset B (internal test set from center 1), and dataset C (external validation test from center 2). Disease-free survival (DFS) data were collected. CT radiomics models were constructed based on four VOIs: gross tumor volume (GTV), 3 mm external to the tumor border (peritumoral volume [PTV]

resultsA total of 334 patients were included (204 and 130 from centers 1 and 2). The model using PTV

conclusionsA radiomics model based on a VOI of 6 mm crossing tumor border more accurately predicts prognosis of clinical stage I solid lung adenocarcinoma than that based on VOIs including overall tumor or external rims of 3 mm and 6 mm. KEY POINTS: • Radiomics is a useful approach to improve the accuracy of prognosis for stage I solid adenocarcinoma. • The radiomics model based on VOIs that includes 3 mm within and external to the tumor border (peritumoral volume [PTV]

Indexed as

Adenocarcinoma of LungLung NeoplasmsHumansPrognosisRetrospective StudiesTomography, X-Ray ComputedAdenocarcinomaLungPeritumoralPrognosisRadiomics

Identifiers

PMID34453574
OpenAlexW3196124991

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.