Evidence map›Paper›PMID 34453564›Full record

SynthesisApplied microbiology and biotechnology2021

Do essential oils from plants occurring in the Brazilian Caatinga biome present antifungal potential against dermatophytoses? A systematic review.

Fillipe de Oliveira Pereira, Anna Paula de Castro Teixeira, Francinalva Dantas de Medeiros

Abstract readSystematic Review
PubMed Publisher
In one paragraph

Synthesis in Applied microbiology and biotechnology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Fillipe de Oliveira PereiraBiochemistry Laboratory, Academic Unit of Health, Education and Health Center, Federal University of Campina Grande, Cuité, Brazil. fillipe.oliveira@professor.ufcg.edu.br.ORCID http://orcid.org/0000-0002-3081-4174
Anna Paula de Castro TeixeiraPostgraduate Program in Development and Technological Innovation in Medicines, Federal University of Paraiba, João Pessoa, Brazil.ORCID http://orcid.org/0000-0002-5252-2850
Francinalva Dantas de MedeirosPharmacognosy Laboratory, Academic Unit of Health, Education and Health Center, Federal University of Campina Grande, Cuité, Brazil.ORCID http://orcid.org/0000-0003-1812-6966

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The Caatinga is an exclusively Brazilian biome where semiarid climatic conditions promote singularities in adaptive biodiversity. Many aromatic species are found in this region possessing antifungal properties, which are attributed to their essential oils. Thus, we questioned whether essential plant oils found in the Caatinga present anti-dermatophytic potential. Dermatophytes are keratinophilic fungi that cause one of the most prevalent mycoses globally, skin infections known as dermatophytoses (tineas). Here, we provide a comprehensive report of the available published information, analyzing the methods used to evaluate the antifungal activity, verifying the quality of the evidence and possible clinical applications, and discussing research trends in this area. The plants studied concentrated in the genera Croton (Euphorbiaceae), Lippia (Verbenaceae), Piper (Piperaceae), and Mentha (Lamiaceae). All of the studies used in vitro tests to analyze antifungal potential, and little evidence was ascertained concerning the mechanism of antifungal action. In addition, the essential oils also evidenced drug modifying activity of conventional antifungal drugs (Ketoconazole and Terbinafine). We believe that the anti-dermatophyte potential of plant essential oils occurring within the Caatinga is underestimated and that this review will encourage future chemical-pharmacological investigations into the plants within this biome.Key points• The essential oils from plants occurring in the Caatinga Biome present unknown anti-dermatophyte potential.• The studies against dermatophyte fungi concentrate on the families Lamiaceae and Verbenaceae.• In vitro assays were used to assess the anti-dermatophyte potential of the essential oils.

Indexed as

Oils, VolatileTineaAntifungal AgentsEcosystemHumansMicrobial Sensitivity TestsPlant OilsAntifungal AgentsOils, VolatilePlant OilsBiodiversityDermatophytesNatural drugsPlantRingwormSemiaridTinea

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.