Evidence map›Paper›PMID 34453523›Full record

ArticleEuropean journal of cardiovascular nursing2022

Adverse events in patients with a left ventricular assist device: are patient-reported outcomes affected?

Jessica Harman Thompson, Kenneth Faulkner, Christopher Lee

Abstract read
In one paragraph

Article in European journal of cardiovascular nursing, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Jessica Harman ThompsonBoston College, Connell School of Nursing, Chestnut Hill, MA, USA.ORCID 0000-0002-4564-9861
Kenneth FaulknerBoston College, Connell School of Nursing, Chestnut Hill, MA, USA.
Christopher LeeBoston College, Connell School of Nursing, Chestnut Hill, MA, USA.

Funding

Oregon Clinical and Translational Research InstituteUL1TR000128 · NCATS · OREGON HEALTH & SCIENCE UNIVERSITY · PI ELLISON, DAVID H · 2012 to 2015
$28.7M
Profiling Biobehavioral Responses to Mechanical Support in Advanced Heart FailureR01NR013492 · NINR · OREGON HEALTH & SCIENCE UNIVERSITY · PI LEE, CHRISTOPHER SEAN · 2012 to 2015
$1.4M
NCATS NIH HHS UL1 TR000128NINR NIH HHS R01 NR013492
6 · The paper itself

Abstract

aimsLeft ventricular assist devices (LVAD) are used to treat advanced heart failure, and the use of these devices in ever increasing, with over 19 000 people having had a device. However, during device therapy over 50% of patients will have some type of major adverse event. The aim of this study was to examine whether having a major adverse event, including major infection and major bleed, would alter patient-reported outcomes over time, including depressive symptoms and health-related quality of life. METHODS AND

resultsT-tests and χ2 analyses were used to determine significant differences between patients who had an adverse event and those who did not. Latent curve growth modelling was used to evaluate change over time in those patients with and without and adverse event. The only difference between those with and without an adverse event was pre-implant depressive symptoms and health-related quality of life. The trajectories of both groups were also similar, with only differences at the pre-implant time point.

conclusionIn response to an adverse event occurring post-LVAD implantation, we found that patient-reported outcomes, including depressive symptoms and health-related quality of life were not significantly impacted.

Indexed as

Heart-Assist DevicesHeart FailureHemorrhageHumansPatient Reported Outcome MeasuresQuality of LifeRetrospective StudiesAdverse eventsDepressionLVADPatient-reported outcomesQuality of lifeVentricular assist device

Identifiers

PMID34453523
PMCPMC8994155

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.