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ArticleInternational orthopaedics2022

Temporal changes in sleep quality and knee function following primary total knee arthroplasty: a prospective study.

Ravi Kumar Mukartihal, Darshan S Angadi, Hitesh J Mangukiya, Naveen Kumar Singh, Sugureshwara Varad, Pradeep A Ramesh, Sharan S Patil

Registry-linked trialAbstract read
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In one paragraph

Article in International orthopaedics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05950646 (Effect of Mini-dose Dexmedetomidine-Esketamine Infusion on Sleep Quality in Older Patients Undergoing Knee or Hip Replacement Surgery), which is not on this map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05950646 phase4completednot on this mapstarted 2024, after this paper: background citation

Effect of Mini-dose Dexmedetomidine-Esketamine Infusion on Sleep Quality in Older Patients Undergoing Knee or Hip Replacement Surgery: A Multicenter Randomized Controlled Trial

TypeinterventionalSponsorPeking University First HospitalRan2024 to 2026Enrolled154ConditionsOld Age, Knee Replacement Surgery, Hip Replacement Surgery, DexmedetomidineArmsDexmedetomidine, Esketamine, Normal saline
3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Observational
  5. Article
  6. [Postoperative Sleep Disturbance in Patients Undergoing Arthroplasty: Risk Prediction Modeling Based on Logistic Regression].Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition · 2023
    Article
  7. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors.

Ravi Kumar MukartihalDepartment of Trauma and Orthopaedics, SPARSH Super Speciality Hospital, 146, Infantry Road, Bangalore, 560001, India.
Darshan S AngadiDepartment of Trauma and Orthopaedics, SPARSH Super Speciality Hospital, 146, Infantry Road, Bangalore, 560001, India. docdarshan@gmail.com.
Hitesh J MangukiyaDepartment of Trauma and Orthopaedics, SPARSH Super Speciality Hospital, 146, Infantry Road, Bangalore, 560001, India.
Naveen Kumar SinghDepartment of Trauma and Orthopaedics, SPARSH Super Speciality Hospital, 146, Infantry Road, Bangalore, 560001, India.
Sugureshwara VaradDepartment of Trauma and Orthopaedics, SPARSH Super Speciality Hospital, 146, Infantry Road, Bangalore, 560001, India.
Pradeep A RameshDepartment of Trauma and Orthopaedics, SPARSH Super Speciality Hospital, 146, Infantry Road, Bangalore, 560001, India.
Sharan S PatilDepartment of Trauma and Orthopaedics, SPARSH Super Speciality Hospital, 146, Infantry Road, Bangalore, 560001, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeSeveral patient-reported outcome measures (PROMs) have been used to assess improvement in the quality of life following total knee arthroplasty (TKA). However, there is paucity of studies evaluating the sleep quality and knee function following TKA. The primary aim of our study was to evaluate the sleep quality and knee function in primary TKA patients using the Pittsburgh Sleep Quality Index (PSQI) and Knee Society Score (KSS), respectively. The secondary aim was to assess the correlation between the two outcome measures over the course of first post-operative year following TKA.

methodsOne hundred sixty-eight patients (female-140/male-28) with mean age of 64.63 years (± 7.50) who underwent 168 primary unilateral TKA using a cemented posterior-stabilised implant without patella resurfacing between June 2018 and October 2018 were included in the study. Global PSQI and KSS were recorded pre-operatively and post-operatively weekly up to six weeks and at one year. Body mass index (BMI) and Charlson comorbidity index (CCI) were recorded during pre-operative assessment.

resultsMean(± SD) BMI and CCI were 28.45(± 4.64) and 2.48(± 0.93), respectively. Pre-operative global PSQI of 1.98(± 0.97) increased to 13.48(± 3.36) in the first post-operative week (p < 0.001) and remained high during all the six weeks following TKA (p < 0.001), whereas at the first post-operative year, it reduced to 2.10(± 1.15) (p = 0.15). Pre-operative KSS of 52.00(± 9.98) increased to 71.67(± 6.58) and 85.49(± 4.67) at 6 weeks and the first post-operative year respectively (p < 0.001). Pre-operative global PSQI had moderate correlation with pre-operative KSS (r = 0.39) (p < 0.001). Strong correlation was noted between pre-operative global PSQI and six week post-operative KSS (r = 0.47) (p < 0.001). Low correlation was noted between pre-operative global PSQI and KSS at the first post-operative year (r = 0.10, p = 0.19) following TKA. Multiple regression analysis revealed age, CCI, and pre-operative range of motion as independent predictors of global PSQI.

conclusionsPatients undergoing TKA experience changes in sleep quality but report an overall improvement in knee function during the first post-operative year. Sleep quality has moderate to strong correlation with knee function in the early post-operative period beyond which there is a low correlation with knee function thereby suggesting a transient phenomenon. Hence patients undergoing TKA can be appropriately counselled regarding the variation in sleep quality in the post-operative period and reassured accordingly.

Indexed as

Arthroplasty, Replacement, KneeOsteoarthritis, KneeFemaleHumansKnee JointMaleMiddle AgedProspective StudiesQuality of LifeSleep QualityTreatment OutcomeArthroplastyFunctionKneeOutcomesSleep

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.