Evidence map›Paper›PMID 34453143›Full record

ArticleNature reviews. Gastroenterology & hepatology2021

International consensus on the prevention of venous and arterial thrombotic events in patients with inflammatory bowel disease.

Pablo A Olivera, Stephane Zuily, Paulo G Kotze, Veronique Regnault, Sameer Al Awadhi, Peter Bossuyt, Richard B Gearry, Subrata Ghosh, Taku Kobayashi, Patrick Lacolley and 9 more

Open access · hybridAbstract readConsensus Statement
In one paragraph

Article in Nature reviews. Gastroenterology & hepatology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 69 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
69citing papers in PubMed, 4 pooled it
18.2field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

69 citing papers in PubMed, 4 syntheses or guidelines pooled it, 140 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Pooled it
  5. Article
  6. Review
  7. Article
  8. Article
  9. Utility of rotational thrombo-elastometry as an objective measure of hypercoagulability in ulcerative colitis.Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology · 2026
    Article
  10. Article
  11. Review
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Review
  19. Article
  20. Article

9 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors at 16 institutions in 12 countries.

Pablo A OliveraGastroenterology Section, Department of Internal Medicine, Centro de Educación Médica e Investigaciones Clínicas (CEMIC), Buenos Aires, Argentina.
Stephane ZuilyVascular Medicine Division and Regional Competence Center for Rare Vascular and Systemic Autoimmune Diseases, Centre Hospitalier Régional Universitaire de Nancy, Vandoeuvre-lès-Nancy, France.ORCID http://orcid.org/0000-0002-9326-6881
Paulo G KotzeIBD outpatient clinics, Colorectal Surgery Unit, Catholic University of Paraná (PUCPR), Curitiba, Brazil.ORCID http://orcid.org/0000-0002-9632-6691
Veronique RegnaultUniversity of Lorraine, INSERM, DCAC, Nancy, France.
Sameer Al AwadhiGastroenterology Division, Rashid Hospital, Dubai Health Authority, Dubai, UAE.
Peter BossuytImelda GI Clinical Research Center, Imelda General Hospital, Bonheiden, Belgium.ORCID http://orcid.org/0000-0003-4027-7365
Richard B GearryDepartment of Medicine, University of Otago, Christchurch, New Zealand.
Subrata GhoshNIHR Biomedical Research Centre, University of Birmingham and University Hospitals NHS Foundation Trust, Birmingham, UK.ORCID http://orcid.org/0000-0002-1713-7797
Taku KobayashiCenter for Advanced IBD Research and Treatment, Kitasato University, Kitasato Institute Hospital, Tokyo, Japan.ORCID http://orcid.org/0000-0002-2073-4234
Patrick LacolleyUniversity of Lorraine, INSERM, DCAC, Nancy, France.
Edouard LouisDepartment of Gastroenterology, CHU Liège University Hospital, Liège, Belgium.
Fernando MagroDepartment of Gastroenterology, Centro Hospitalar São João, Porto, Portugal.
Siew C NgDepartment of Medicine and Therapeutics, Institute of Digestive Disease, LKS Institute of Health Science, The Chinese University of Hong Kong, Hong Kong SAR, China.ORCID http://orcid.org/0000-0002-6850-4454
Alfredo PapaDivision of Internal Medicine and Gastroenterology, Fondazione Policlinico Universitario "A. Gemelli" IRCCS, Rome, Italy.ORCID http://orcid.org/0000-0002-4186-7298
Tim RaineDepartment of Gastroenterology, Cambridge University Hospitals NHS Foundation Trust, Cambridge, UK.ORCID http://orcid.org/0000-0002-5855-9873
Fabio V TeixeiraGastrosaúde - IBD Clinic, Marília, SP, Brazil.
David T RubinUniversity of Chicago Medicine, Inflammatory Bowel Disease Center, Chicago, IL, USA.ORCID http://orcid.org/0000-0001-5647-1723
Silvio DaneseIBD Center, Department of Gastroenterology, Humanitas Clinical and Research Center - IRCCS, Milan, Italy.ORCID http://orcid.org/0000-0001-7341-1351
Laurent Peyrin-BirouletDepartment of Gastroenterology and INSERM NGERE U1256, University Hospital of Nancy, University of Lorraine, Vandoeuvre-lès-Nancy, France. peyrinbiroulet@gmail.com.ORCID http://orcid.org/0000-0003-2536-6618
Inserm · FRCambridge University Hospitals NHS Foundation Trust · GBCentro de Educación Médica e Investigaciones Clínicas Norberto Quirno · ARChinese University of Hong Kong · HKDubai Health Authority · AEFaculdade de Medicina de Marília · BRHospital de São João · PTHumanitas University · ITImelda Hospital · BEKitasato Institute Hospital · JPNIHR Birmingham Biomedical Research Centre · GBPontifícia Universidade Católica do Paraná · BRUniversità Cattolica del Sacro Cuore · ITUniversity of Chicago · USUniversity of Liège · BEUniversity of Otago · NZ

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Patients with inflammatory bowel disease (IBD) are at increased risk of thrombotic events. Therapies for IBD have the potential to modulate this risk. The aims of this Evidence-Based Guideline were to summarize available evidence and to provide practical recommendations regarding epidemiological aspects, prevention and drug-related risks of venous and arterial thrombotic events in patients with IBD. A virtual meeting took place in May 2020 involving 14 international IBD experts and 3 thrombosis experts from 12 countries. Proposed statements were voted upon in an anonymous manner. Agreement was defined as at least 75% of participants voting as 'fully agree' or 'mostly agree' with each statement. For each statement, the level of evidence was graded according to the Scottish Intercollegiate Guidelines Network (SIGN) grading system. Consensus was reached for 19 statements. Patients with IBD harbour an increased risk of venous and arterial thrombotic events. Thromboprophylaxis is indicated during hospitalization of any cause in patients with IBD. Disease activity is a modifiable risk factor in patients with IBD, and physicians should aim to achieve deep remission to reduce the risk. Exposure to steroids should be limited. Antitumour necrosis factor agents might be associated with a reduced risk of thrombotic events.

Indexed as

Anti-Inflammatory AgentsFibrinolytic AgentsHospitalizationHumansInflammatory Bowel DiseasesInternational CooperationPatient AcuityRisk AssessmentRisk FactorsThrombosisAnti-Inflammatory AgentsFibrinolytic Agents

Identifiers

PMID34453143
PMCPMC8395387
OpenAlexW3196088619

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.