Evidence map›Paper›PMID 34453114›Full record

Trial reportBritish journal of cancer2021

Randomised controlled trial and economic evaluation of a targeted cancer awareness intervention for adults living in deprived areas of the UK.

Yvonne Moriarty, Mandy Lau, Bernadette Sewell, Rob Trubey, Harriet Quinn-Scoggins, Sioned Owen, Louise Padgett, Vasiliki Kolovou, Julie Hepburn, Peter Buckle and 13 more

Open access · hybridAbstract readRandomized Controlled Trial
In one paragraph

Trial report in British journal of cancer, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.4field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Review
  3. The burden of acute eye conditions on different healthcare providers: a retrospective population-based study.The British journal of general practice : the journal of the Royal College of General Practitioners · 2024
    Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

23 authors at 9 institutions in 1 country.

Yvonne MoriartyCentre for Trials Research, Cardiff University, Cardiff, UK. MoriartyY@cardiff.ac.uk.ORCID http://orcid.org/0000-0002-7608-4699
Mandy LauCentre for Trials Research, Cardiff University, Cardiff, UK.
Bernadette SewellSwansea Centre for Health Economics, College of Human and Health Sciences, Swansea University, Swansea, UK.ORCID http://orcid.org/0000-0001-5471-922X
Rob TrubeyCentre for Trials Research, Cardiff University, Cardiff, UK.
Harriet Quinn-ScogginsPRIME Centre Wales, Division of Population Medicine, School of Medicine, Cardiff University, Cardiff, UK.
Sioned OwenTenovus Cancer Care, Cardiff, UK.
Louise PadgettDepartment of Health Sciences, University of York, York, UK.
Vasiliki KolovouSchool of Sport & Health Sciences, Cardiff Metropolitan University, Cardiff, UK.
Julie HepburnPublic Involvement Community, Health and Care Research Wales Support Centre, Cardiff, UK.
Peter BuckleMarie Curie Research Voices, London, UK.
Rebecca PlayleCentre for Trials Research, Cardiff University, Cardiff, UK.
Julia TownsonCentre for Trials Research, Cardiff University, Cardiff, UK.
Michael RoblingCentre for Trials Research, Cardiff University, Cardiff, UK.
Stephanie GilbertCentre for Trials Research, Cardiff University, Cardiff, UK.
Polyxeni DimitropoulouCentre for Trials Research, Cardiff University, Cardiff, UK.
Adrian EdwardsPRIME Centre Wales, Division of Population Medicine, School of Medicine, Cardiff University, Cardiff, UK.
Caroline MitchellAcademic Unit of Primary Medical Care, University of Sheffield, Northern General Hospital, Sheffield, UK.
Maura MatthewsTenovus Cancer Care, Cardiff, UK.
Stephanie SmitsPRIME Centre Wales, Division of Population Medicine, School of Medicine, Cardiff University, Cardiff, UK.
Fiona WoodPRIME Centre Wales, Division of Population Medicine, School of Medicine, Cardiff University, Cardiff, UK.
Richard D NealLeeds Institute of Health Sciences, University of Leeds, Leeds, UK.
Kate BrainPRIME Centre Wales, Division of Population Medicine, School of Medicine, Cardiff University, Cardiff, UK.
ABACus study team
Cardiff University · GBSwansea University · GBTenovus Cancer Care · GBCardiff Metropolitan University · GBHealth and Care Research Wales · GBMarie Curie · GBNorthern General Hospital · GBUniversity of Leeds · GBUniversity of York · GB

Funding

Cancer Research UK 25350
6 · The paper itself

Abstract

backgroundCancer outcomes are poor in socioeconomically deprived communities, with low symptom awareness contributing to prolonged help-seeking and advanced disease. Targeted cancer awareness interventions require evaluation.

methodsThis is a randomised controlled trial involving adults aged 40+ years recruited in community and healthcare settings in deprived areas of South Yorkshire and South-East Wales.

interventionpersonalised behavioural advice facilitated by a trained lay advisor. CONTROL: usual care. Follow-up at two weeks and six months post-randomisation. PRIMARY OUTCOME: total cancer symptom recognition score two weeks post-randomisation.

resultsTwo hundred and thirty-four participants were randomised. The difference in total symptom recognition at two weeks [adjusted mean difference (AMD) 0.6, 95% CI: -0.03, 1.17, p = 0.06] was not statistically significant. Intervention participants reported increased symptom recognition (AMD 0.8, 95% CI: 0.18, 1.37, p = 0.01) and earlier intended presentation (AMD -2.0, 95% CI: -3.02, -0.91, p < 0.001) at six months. "Lesser known" symptom recognition was higher in the intervention arm (2 weeks AMD 0.5, 95% CI: 0.03, 0.97 and six months AMD 0.7, 95% CI: 0.16, 1.17). Implementation cost per participant was £91.34, with no significant between-group differences in healthcare resource use post-intervention.

conclusionsImproved symptom recognition and earlier anticipated presentation occurred at longer-term follow-up. The ABACus Health Check is a viable low-cost intervention to increase cancer awareness in socioeconomically deprived communities. CLINICAL

trial registrationISRCTN16872545.

Indexed as

Health Knowledge, Attitudes, PracticeNeoplasmsAdultCost-Benefit AnalysisFemaleHealthcare DisparitiesHealth PromotionHumansMaleMedically Underserved AreaMiddle AgedPoverty AreasSurveys and QuestionnairesUnited Kingdom

Identifiers

PMID34453114
PMCPMC8391006
OpenAlexW3195764025

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.