Evidence map›Paper›PMID 34452694›Full record

ReviewAdvances in pharmacology (San Diego, Calif.)2021

The new kids on the block: Emerging obesogens.

Raquel Chamorro-Garcia, Almudena Veiga-Lopez

Open access · greenAbstract readReview
In one paragraph

Review in Advances in pharmacology (San Diego, Calif.), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
7.0field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 17 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

Raquel Chamorro-GarciaDepartment of Microbiology and Environmental Toxicology, University of California Santa Cruz, Santa Cruz, CA, United States. Electronic address: rchamorr@ucsc.edu.
Almudena Veiga-LopezDepartment of Pathology, University of Illinois-Chicago, Chicago, IL, United States; The ChicAgo Center for Health and Environment, University of Illinois at Chicago, Chicago, IL, United States. Electronic address: veiga@uic.edu.
University of California, Santa Cruz · USUniversity of Illinois Chicago · US

Funding

Pilot Program CoreP30ES027792 · NIEHS · UNIVERSITY OF CHICAGO · PI RICHARD D MINSHALL · 2017 to 2026
$13.6M
UCSF Environmental Research and Translation for Health Center (EaRTH Center)P30ES030284 · NIEHS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI JENNIFER C FUNG, Tracey J. Woodruff · 2020 to 2026
$11.2M
Placental adaptive mechanisms to environmental exposures.R01ES027863 · NIEHS · UNIVERSITY OF ILLINOIS AT CHICAGO · PI VEIGA-LOPEZ, ALMUDENA · 2018 to 2022
$1.9M
Environmental Programming of Insulin ResistanceK22ES026208 · NIEHS · MICHIGAN STATE UNIVERSITY · PI VEIGA-LOPEZ, ALMUDENA · 2016 to 2018
$464k
NIEHS NIH HHS K22 ES026208NIEHS NIH HHS P30 ES027792NIEHS NIH HHS P30 ES030284NIEHS NIH HHS R01 ES027863
6 · The paper itself

Abstract

The current obesity epidemic is calling for action in the determination of contributing factors. Although social and life-style factors have been traditionally associated with metabolic disruption, a subset of endocrine-disrupting chemicals (EDCs), called obesogens are garnering increasing attention for their ability to promote adipose tissue differentiation and accumulation. For some chemicals, such as tributyltin, there is conclusive evidence regarding their ability to promote adipogenesis and their mechanism of action. In recent years, the list of chemicals that exert obesogenic potential is increasing. In this chapter, we review current knowledge of the most recent developments in the field of emerging obesogens with a specific focus on food additives, surfactants, and sunscreens, for which the mechanism of action remains unclear. We also review new evidence relative to the obesogenic potential of environmentally relevant chemical mixtures and point to potential therapeutic approaches to minimize the detrimental effects of obesogens. We conclude by discussing the available tools to investigate new obesogenic chemicals, strategies to maximize reproducibility in adipogenic studies, and future directions that will help propel the field forward.

Indexed as

Endocrine DisruptorsAdipogenesisHumansObesityReproducibility of ResultsEndocrine DisruptorsAdipogenesisAdipose tissueEmerging obesogensEndocrine disrupting chemicalsFood additives

Identifiers

PMID34452694
PMCPMC8941623
OpenAlexW3195651302

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.