Evidence map›Paper›PMID 34452556›Full record

Observational studyAsian Pacific journal of cancer prevention : APJCP2021

Prevalence of Trismus and Its Impact on Oral Health-Related Quality of Life in Patients Treated for Oral Squamous Cell Carcinoma.

Shailesh M Gondivkar, Amol R Gadbail, Sachin C Sarode, Subhrajit Dasgupta, Balkrishna Sharma, Amol Hedaoo, Aparna Sharma, Gargi S Sarode, Monal Yuwanati, Rima S Gondivkar and 2 more

Open access · goldAbstract readObservational Study
In one paragraph

Observational study in Asian Pacific journal of cancer prevention : APJCP, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
2.2field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 22 citations in OpenAlex.

  1. Article
  2. The Role of Dental Oncology in Cancer Care: a Critical Component of Comprehensive Treatment, Education, and Interdisciplinary Collaboration- a Narrative Review.Journal of cancer education : the official journal of the American Association for Cancer Education · 2026
    Review
  3. Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. Histomorphometric Analysis of Oral Squamous Cell Carcinoma, Apparently Normal Adjacent Mucosa and Epithelial Dysplasia.Indian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India · 2024
    Article
  9. Article
  10. Article
  11. Review
  12. Article
  13. Review
  14. Development and Feasibility of CALORIE CAREIndian journal of palliative care
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 6 institutions in 2 countries.

Shailesh M GondivkarDepartment of Oral Medicine & Radiology, Government Dental College & Hospital, Nagpur, Maharashtra, India.
Amol R GadbailDepartment of Dentistry, Indira Gandhi Government Medical College & Hospital, Nagpur, Maharashtra State, India.ORCID 0000-0002-6546-7694
Sachin C SarodeDepartment of Oral Pathology & Microbiology, Dr. D.Y. Patil Dental College & Hospital, Dr. D.Y. Patil Vidyapeeth, Pune, Maharashtra State, India.ORCID 0000-0003-1856-0957
Subhrajit DasguptaRST Cancer Hospital & Research Centre (Tertiary care cancer centre), Nagpur, Maharashtra State, India.
Balkrishna SharmaRST Cancer Hospital & Research Centre (Tertiary care cancer centre), Nagpur, Maharashtra State, India.
Amol HedaooRST Cancer Hospital & Research Centre (Tertiary care cancer centre), Nagpur, Maharashtra State, India.
Aparna SharmaDepartment of Dentistry, Government Medical College & Hospital, Nagpur, Maharashtra State, India.
Gargi S SarodeDepartment of Oral Pathology & Microbiology, Dr. D.Y. Patil Dental College & Hospital, Dr. D.Y. Patil Vidyapeeth, Pune, Maharashtra State, India.
Monal YuwanatiDepartment of Oral Pathology and Microbiology. Saveetha Dental College and Hospitals, Saveetha Institute of Medical and Technical Sciences, Saveetha University, Chennai, India.ORCID 0000-0001-9233-8292
Rima S GondivkarDental Surgeon, , Aarti regency, Mahalakshmi Nagar, Manewada Road, Nagpur, Maharashtra State, India.
Shankargouda PatilDepartment of Diagnostic Sciences, Division of Oral Pathology, College of Dentistry, Jazan University, Jazan, Kingdom of Saudi Arabia.ORCID 0000-0001-7246-5497
Rahul N GaikwadDepartment of Community Dentistry and Oral Epidemiology, College of Dentistry, Qassim University, Buraydah, Kingdom of Saudi Arabia.
Dr. D.Y. Patil Vidyapeeth, Pune · INGovernment Dental College and Hospital · INGovernment Medical College and Hospital · INIndira Gandhi Government Medical College & Hospital · INJazan University · SAQassim University · SA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Oral squamous cell carcinoma, one of the most common malignancies, has a poor prognosis due to impairment in oral functions secondary to treatment. Trismus one of the major causes of impairment of oral function. The present study investigated the prevalence of trismus and its impact on oral health-related quality of life (OHRQoL) in patients treated for oral squamous cell carcinoma (OSCC). The maximum inter-incisal mouth opening of hundred OSCC patients was recorded at post-treatment and 3 months post-treatment. OHRQoL questionnaire (OHIP-14) was intervened to assess the OHRQoL of patients post-treatment and 3 months follow-up, with emphasis on correlation with grades of trismus. The prevalence of trismus was 16% pre-treatment, 72% post-treatment, and 62% at 3 months after treatment. The overall OHIP-14 scores indicated that patients with trismus reported greater impairment of OHRQoL than those without trismus at the end of treatment and 3 months follow-up. At the end of treatment, patients with severe trismus demonstrated a higher mean OHIP-14 score (23.47 ±3.34) than those with moderate (17.72 ±2.83) and mild trismus (12.66 ±3.84) with statistically significant differences (p <0.001). Equivalent results were obtained at 3 months follow-up period. Patients with trismus suffer greater impairment of OHRQoL. The findings demand the need of identifying risk factors for developing trismus and early institution of newer/modified treatment approaches for better OHRQoL in OSCC survivors.<br />.

Indexed as

Oral HealthQuality of LifeCarcinoma, Squamous CellCombined Modality TherapyCross-Sectional StudiesFemaleFollow-Up StudiesHumansMaleMiddle AgedMouth NeoplasmsPrevalencePrognosisProspective StudiesSurveys and QuestionnairesSurvival RateOHIP-14oral health-related quality of lifeoral squamous cell carcinomaQuality of Lifetrismus

Identifiers

PMID34452556
PMCPMC8629467
OpenAlexW3194174015

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.