Evidence map›Paper›PMID 34452522›Full record

ReviewViruses2021

Cross Talk between Viruses and Insect Cells Cytoskeleton.

Ayda Khorramnejad, Hugo D Perdomo, Umberto Palatini, Mariangela Bonizzoni, Laila Gasmi

Open access · goldAbstract readReview
In one paragraph

Review in Viruses, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
4.4field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 25 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Proteomics analysis of soluble secreted proteins ofFrontiers in cellular and infection microbiology · 2025
    Article
  6. Article
  7. Article
  8. Cytoskeleton-associated gelsolin responds to the midgut distention process in saline meal-fed Aedes aegypti and affects arbovirus dissemination from the midgut.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2024
    Article
  9. Article
  10. Article
  11. A database of crop pest cell lines.In vitro cellular & developmental biology. Animal · 2022
    Article
  12. Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Ayda KhorramnejadDepartment of Biology and Biotechnology, University of Pavia, Via Ferrata 9, 27100 Pavia, Italy.ORCID 0000-0003-1110-5791
Hugo D PerdomoDepartment of Biology and Biotechnology, University of Pavia, Via Ferrata 9, 27100 Pavia, Italy.ORCID 0000-0002-8783-1557
Umberto PalatiniDepartment of Biology and Biotechnology, University of Pavia, Via Ferrata 9, 27100 Pavia, Italy.ORCID 0000-0002-2435-2655
Mariangela BonizzoniDepartment of Biology and Biotechnology, University of Pavia, Via Ferrata 9, 27100 Pavia, Italy.
Laila GasmiDepartment of Biology and Biotechnology, University of Pavia, Via Ferrata 9, 27100 Pavia, Italy.ORCID 0000-0003-1553-8252
University of Pavia · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Viruses are excellent manipulators of host cellular machinery, behavior, and life cycle, with the host cell cytoskeleton being a primordial viral target. Viruses infecting insects generally enter host cells through clathrin-mediated endocytosis or membrane fusion mechanisms followed by transport of the viral particles to the corresponding replication sites. After viral replication, the viral progeny egresses toward adjacent cells and reaches the different target tissues. Throughout all these steps, actin and tubulin re-arrangements are driven by viruses. The mechanisms used by viruses to manipulate the insect host cytoskeleton are well documented in the case of alphabaculoviruses infecting Lepidoptera hosts and plant viruses infecting Hemiptera vectors, but they are not well studied in case of other insect-virus systems such as arboviruses-mosquito vectors. Here, we summarize the available knowledge on how viruses manipulate the insect host cell cytoskeleton, and we emphasize the primordial role of cytoskeleton components in insect virus motility and the need to expand the study of this interaction.

Indexed as

AnimalsCytoskeletonHost-Pathogen InteractionsInsectaInsect Virusesbaculoviruscytoskeletonvector–virus interactionsvirus motility

Identifiers

PMID34452522
PMCPMC8402729
OpenAlexW3195382637

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.