Evidence map›Paper›PMID 34452497›Full record

ArticleViruses2021

Serological Screening for Antibodies against SARS-CoV-2 in Dutch Shelter Cats.

W J R van der Leij, Els M Broens, Jan Willem Hesselink, Nancy Schuurman, Johannes C M Vernooij, Herman F Egberink

Open access · goldAbstract read
In one paragraph

Article in Viruses, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
1.5field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 27 citations in OpenAlex.

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  12. SARS-CoV-2 Seroprevalence Studies in Pets, Spain.Emerging infectious diseases · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

W J R van der LeijDepartment of Clinical Sciences, Shelter Medicine Program, Faculty of Veterinary Medicine, Utrecht University, Yalelaan 108, 3584 CM Utrecht, The Netherlands.
Els M BroensVeterinary Microbiological Diagnostic Centre (VMDC), Department of Biomolecular Health Sciences, Faculty of Veterinary Medicine, Utrecht University, Yalelaan 1, 3584 CL Utrecht, The Netherlands.ORCID 0000-0003-1312-6115
Jan Willem HesselinkDepartment of Clinical Sciences, Faculty of Veterinary Medicine, Utrecht University, Yalelaan 108, 3584 CM Utrecht, The Netherlands.
Nancy SchuurmanVirology Division, Department of Biomolecular Health Sciences, Faculty of Veterinary Medicine, Utrecht University, Yalelaan 1, 3584 CL Utrecht, The Netherlands.
Johannes C M VernooijDepartment of Population Health Sciences, Faculty of Veterinary Medicine, Utrecht University, Yalelaan 7, 3584 CL Utrecht, The Netherlands.ORCID 0000-0002-2646-9216
Herman F EgberinkVirology Division, Department of Biomolecular Health Sciences, Faculty of Veterinary Medicine, Utrecht University, Yalelaan 1, 3584 CL Utrecht, The Netherlands.ORCID 0000-0001-6852-5936
Utrecht University · NL

Funding

Dutch Ministry of Agriculture, Nature and Food Quality and the Dutch Ministry of Health, Welfare and Sport. not available
6 · The paper itself

Abstract

The COVID-19 pandemic raised concerns that companion animals might be infected with, and could become a reservoir of, SARS-CoV-2. As cats are popular pets and susceptible to Coronavirus, we investigated the seroprevalence of SARS-CoV-2 antibodies in shelter cats housed in Dutch animal shelters during the COVID-19 pandemic. In this large-scale cross-sectional study, serum samples of shelter cats were collected during the second wave of human COVID-19 infections in The Netherlands. Seroprevalence was determined by using an indirect protein-based ELISA validated for cats, and a Virus Neutralization Test (VNT) as confirmation. To screen for feline SARS-CoV-2 shedding, oropharyngeal and rectal swabs of cats positive for ELISA and/or VNT were analyzed using PCR tests. In 28 Dutch animal shelters, 240 shelter cats were convenience sampled. Two of these cats (0.8%; CI 95%: 0.1-3.0%) were seropositive, as evidenced by the presence of SARS-CoV-2 neutralizing antibodies. The seropositive animals tested PCR negative for SARS-CoV-2. Based on the results of this study, it is unlikely that shelter cats could be a reservoir of SARS-CoV-2 or pose a (significant) risk to public health.

Indexed as

AnimalsAntibodies, NeutralizingAntibodies, ViralCat DiseasesCatsCOVID-19COVID-19 Nucleic Acid TestingCOVID-19 Serological TestingCross-Sectional StudiesFemaleHousing, AnimalHumansMaleNetherlandsSARS-CoV-2Seroepidemiologic StudiesAntibodies, NeutralizingAntibodies, Viralanimal shelterCoronavirus disease 2019 (COVID-19)neutralizing SARS-CoV-2 antibodyone healthserologyseroprevalenceshelter medicinetiter

Identifiers

PMID34452497
PMCPMC8402678
OpenAlexW3194619083

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.