Evidence map›Paper›PMID 34452480›Full record

ArticleViruses2021

What Binds Cationic Photosensitizers Better: Brownian Dynamics Reveals Key Interaction Sites on Spike Proteins of SARS-CoV, MERS-CoV, and SARS-CoV-2.

Vladimir Fedorov, Ekaterina Kholina, Sergei Khruschev, Ilya Kovalenko, Andrew Rubin, Marina Strakhovskaya

Open access · goldAbstract read
In one paragraph

Article in Viruses, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.7field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 15 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Vladimir FedorovFaculty of Biology, Lomonosov Moscow State University, 119234 Moscow, Russia.ORCID 0000-0002-9397-1548
Ekaterina KholinaFaculty of Biology, Lomonosov Moscow State University, 119234 Moscow, Russia.ORCID 0000-0002-5918-5084
Sergei KhruschevFaculty of Biology, Lomonosov Moscow State University, 119234 Moscow, Russia.
Ilya KovalenkoFaculty of Biology, Lomonosov Moscow State University, 119234 Moscow, Russia.
Andrew RubinFaculty of Biology, Lomonosov Moscow State University, 119234 Moscow, Russia.
Marina StrakhovskayaFaculty of Biology, Lomonosov Moscow State University, 119234 Moscow, Russia.ORCID 0000-0002-4571-0431
Lomonosov Moscow State University · RUPeoples' Friendship University of Russia · RU

Funding

Russian Foundation for Basic Research 20-04-60084
6 · The paper itself

Abstract

We compared the electrostatic properties of the spike proteins (S-proteins) of three coronaviruses, SARS-CoV, MERS-CoV, and SARS-CoV-2, and their interactions with photosensitizers (PSs), octacationic octakis(cholinyl)zinc phthalocyanine (Zn-PcChol

Indexed as

Binding SitesCholineIndolesIsoindolesMethylene BlueMiddle East Respiratory Syndrome CoronavirusModels, MolecularMolecular Dynamics SimulationOrganometallic CompoundsPhotosensitizing AgentsProtein ConformationProtein DomainsProtein SubunitsSARS-CoV-2Severe acute respiratory syndrome-related coronavirusSpike Glycoprotein, CoronavirusCholineIndolesIsoindolesMethylene Blueoctacationic octakis(cholinyl)zinc phthalocyanineOrganometallic CompoundsPhotosensitizing AgentsProtein SubunitsSpike Glycoprotein, Coronavirusspike glycoprotein, SARS-CoVspike protein, SARS-CoV-2Zinc CompoundsZn(II)-phthalocyanineBrownian dynamicsMERS-CoVmethylene blueoctakis(cholinyl)zinc phthalocyaninephotosensitizerSARS-CoVSARS-CoV-2spike protein

Identifiers

PMID34452480
PMCPMC8402653
OpenAlexW3194199527

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.