Evidence map›Paper›PMID 34452264›Full record

ArticlePharmaceutics2021

Optimization and Evaluation of the In Vitro Permeation Parameters of Topical Products with Non-Steroidal Anti-Inflammatory Drugs through Strat-M

Bartłomiej Milanowski, Hanna Wosicka-Frąckowiak, Eliza Główka, Małgorzata Sosnowska, Stanisław Woźny, Filip Stachowiak, Angelika Suchenek, Dariusz Wilkowski

Open access · goldAbstract read
In one paragraph

Article in Pharmaceutics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
1.7field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 30 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Bartłomiej MilanowskiChair and Department of Pharmaceutical Technology, Poznan University of Medical Sciences, ul. Grunwaldzka 6, 60-780 Poznań, Poland.ORCID 0000-0002-6450-174X
Hanna Wosicka-FrąckowiakChair and Department of Pharmaceutical Technology, Poznan University of Medical Sciences, ul. Grunwaldzka 6, 60-780 Poznań, Poland.
Eliza GłówkaChair and Department of Pharmaceutical Technology, Poznan University of Medical Sciences, ul. Grunwaldzka 6, 60-780 Poznań, Poland.ORCID 0000-0002-8646-4636
Małgorzata SosnowskaGENERICA Pharmaceutical Lab, Regionalne Centrum Zdrowia Sp. z o. o., ul. Na Kępie 3, 64-360 Zbąszyń, Poland.
Stanisław WoźnyGENERICA Pharmaceutical Lab, Regionalne Centrum Zdrowia Sp. z o. o., ul. Na Kępie 3, 64-360 Zbąszyń, Poland.
Filip StachowiakGENERICA Pharmaceutical Lab, Regionalne Centrum Zdrowia Sp. z o. o., ul. Na Kępie 3, 64-360 Zbąszyń, Poland.
Angelika SuchenekMYLAN Healthcare Sp. z o. o., ul. Postępu 21B, 02-676 Warszawa, Poland.
Dariusz WilkowskiMYLAN Healthcare Sp. z o. o., ul. Postępu 21B, 02-676 Warszawa, Poland.
Poznan University of Medical Sciences · PL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Pharmaceutical products containing non-steroidal anti-inflammatory drugs (NSAIDs) are among the most prescribed topical formulations used for analgesic and antirheumatic properties. These drugs must overcome the skin barrier to cause a therapeutic effect. Human skin has been widely used as a model to study in vitro drug diffusion and permeation, however, it suffers from many limitations. Therefore, to perform in vitro permeation test (IVPT), we used a Strat-M

Indexed as

diclofenacetofenamateibuprofenin vitro permeation testketoprofennaproxenPlackett–Burman designStrat-M® membrane

Identifiers

PMID34452264
PMCPMC8398299
OpenAlexW3193787212

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.