Evidence map›Paper›PMID 34452250›Full record

ArticlePharmaceutics2021

Optimization of Production Parameters for Andrographolide-Loaded Nanoemulsion Preparation by Microfluidization and Evaluations of Its Bioactivities in Skin Cancer Cells and UVB Radiation-Exposed Skin.

Rathapon Asasutjarit, Nawarat Sooksai, Adryan Fristiohady, Kriyapa Lairungruang, Shiow-Fern Ng, Asira Fuongfuchat

Open access · goldAbstract read
In one paragraph

Article in Pharmaceutics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 1 pooled it
3.6field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 1 synthesis or guideline pooled it, 44 citations in OpenAlex.

  1. Pooled it
  2. Molecules (Basel, Switzerland) · 2026
    Article
  3. Review
  4. Review
  5. Exploring the Active Constituents ofAntioxidants (Basel, Switzerland) · 2025
    Article
  6. Nanoemulsions in Skin Cancer Therapy: A Promising Frontier.Current pharmaceutical biotechnology · 2025
    Review
  7. Article
  8. Development and Optimization ofPharmaceutics · 2024
    Article
  9. Review
  10. Review
  11. Article
  12. Review
  13. Review
  14. Article
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 3 countries.

Rathapon AsasutjaritThammasat University Research Unit in Drug, Health Product Development and Application (DHP-DA), Department of Pharmaceutical Sciences, Faculty of Pharmacy, Thammasat University, Pathum Thani 12120, Thailand.
Nawarat SooksaiThammasat University Research Unit in Drug, Health Product Development and Application (DHP-DA), Department of Pharmaceutical Sciences, Faculty of Pharmacy, Thammasat University, Pathum Thani 12120, Thailand.
Adryan FristiohadyThammasat University Research Unit in Drug, Health Product Development and Application (DHP-DA), Department of Pharmaceutical Sciences, Faculty of Pharmacy, Thammasat University, Pathum Thani 12120, Thailand.ORCID 0000-0002-3499-0511
Kriyapa LairungruangDepartment of Applied Thai Traditional Medicine, Praboromarajchanok Institute, Abhaibhubejhr College of Thai Traditional Medicine Prachinburi, Prachinburi 25230, Thailand.
Shiow-Fern NgCentre for Drug Delivery Technology, Faculty of Pharmacy, University Kebangsaan Malaysia, Jalan Raja Muda Abdul Aziz, Kuala Lumpur 50300, Malaysia.
Asira FuongfuchatNational Metal and Materials Technology Center, National Science and Technology Development Agency (NSTDA), Thailand Science Park, Pathum Thani 12120, Thailand.
Thammasat University · THNational Science and Technology Development Agency · THUniversity Kebangsaan Malaysia Medical Centre · MY

Funding

Thammasat Posdoctoral Fellowship 2021 Grant No. 2-2021Thammasat University Research Fund under the Graduate Grant TUGG 115/2562Thammasat University Research Unit in Drug, Health Product Development and Application (DHP-DA) Project ID. 6305001The Research Fund of Faculty of Pharmacy, Thammasat University under the Specialized Grant, Novel Drug Delivery Systems Development Center TU-S 2/2019
6 · The paper itself

Abstract

Andrographolide (AG) is an active compound isolated from

Indexed as

andrographolidecentral composite designdesign of experimentmicrofluidizationnanoemulsionoptimizationskin cancertransdermal drug deliverytyrosinase inhibitorUVB irradiation

Identifiers

PMID34452250
PMCPMC8399116
OpenAlexW3196127096

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.