Evidence map›Paper›PMID 34452233›Full record

ArticlePharmaceutics2021

The Influence of Omeprazole on the Dissolution Processes of pH-Dependent Magnetic Tablets Assessed by Pharmacomagnetography.

Guilherme A Soares, Deivid W Pires, Leonardo A Pinto, Gustavo S Rodrigues, André G Prospero, Gabriel G A Biasotti, Gabriela N Bittencourt, Erick G Stoppa, Luciana A Corá, Ricardo B Oliveira and 1 more

Open access · goldAbstract read
In one paragraph

Article in Pharmaceutics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.6field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 8 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 1 country.

Guilherme A SoaresDepartment of Biophysics and Pharmacology, Institute of Biosciences, São Paulo State University-UNESP, Botucatu 18618-689, São Paulo, Brazil.ORCID 0000-0002-4723-466X
Deivid W PiresDepartment of Biophysics and Pharmacology, Institute of Biosciences, São Paulo State University-UNESP, Botucatu 18618-689, São Paulo, Brazil.
Leonardo A PintoDepartment of Biophysics and Pharmacology, Institute of Biosciences, São Paulo State University-UNESP, Botucatu 18618-689, São Paulo, Brazil.
Gustavo S RodriguesDepartment of Biophysics and Pharmacology, Institute of Biosciences, São Paulo State University-UNESP, Botucatu 18618-689, São Paulo, Brazil.
André G ProsperoDepartment of Biophysics and Pharmacology, Institute of Biosciences, São Paulo State University-UNESP, Botucatu 18618-689, São Paulo, Brazil.
Gabriel G A BiasottiDepartment of Biophysics and Pharmacology, Institute of Biosciences, São Paulo State University-UNESP, Botucatu 18618-689, São Paulo, Brazil.
Gabriela N BittencourtDepartment of Biophysics and Pharmacology, Institute of Biosciences, São Paulo State University-UNESP, Botucatu 18618-689, São Paulo, Brazil.
Erick G StoppaDepartment of Biophysics and Pharmacology, Institute of Biosciences, São Paulo State University-UNESP, Botucatu 18618-689, São Paulo, Brazil.ORCID 0000-0002-0903-6021
Luciana A CoráCenter of Integrative Sciences, Alagoas State University of Health Sciences-UNCISAL, Maceio 57010-382, Alagoas, Brazil.ORCID 0000-0001-8242-3653
Ricardo B OliveiraSchool of Medicine of Ribeirão Preto, University of São Paulo, Ribeirão Preto 18618-689, São Paulo, Brazil.ORCID 0000-0002-2487-5376
José R A MirandaDepartment of Biophysics and Pharmacology, Institute of Biosciences, São Paulo State University-UNESP, Botucatu 18618-689, São Paulo, Brazil.
Universidade Estadual Paulista (Unesp) · BRUniversidade de São Paulo · BRUniversidade Estadual de Ciências da Saúde de Alagoas · BR

Funding

Fundação de Amparo à Pesquisa do Estado de São Paulo 2015/1492.3-9The National Council for Scientific and Technological Development) 312074/2018-9
6 · The paper itself

Abstract

Pharmacomagnetography involves the simultaneous assessment of solid dosage forms (SDFs) in the human gastrointestinal (GI) tract and the drug plasmatic concentration, using a biomagnetic technique and pharmacokinetics analysis. This multi-instrumental approach helps the evaluation, as GI variables can interfere with the drug delivery processes. This study aimed to employ pharmacomagnetography to evaluate the influence of omeprazole on the drug release and absorption of metronidazole administered orally in magnetic-coated tablets. Magnetic-coated tablets, coated with Eudragit

Indexed as

AC biosusceptometryEudragit® E-100pharmacomagnetographyproton pump inhibitor

Identifiers

PMID34452233
PMCPMC8399305
OpenAlexW3194274888

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.