Evidence map›Paper›PMID 34452219›Full record

ArticlePharmaceutics2021

Iron Oxide Incorporated Conjugated Polymer Nanoparticles for Simultaneous Use in Magnetic Resonance and Fluorescent Imaging of Brain Tumors.

Nuria Arias-Ramos, Luis Exequiel Ibarra, María Serrano-Torres, Balbino Yagüe, Matías Daniel Caverzán, Carlos Alberto Chesta, Rodrigo Emiliano Palacios, Pilar López-Larrubia

Open access · goldAbstract read
In one paragraph

Article in Pharmaceutics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
2.9field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 49 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 2 countries.

Nuria Arias-RamosInstituto de Investigaciones Biomédicas "Alberto Sols", Consejo Superior de Investigaciones Científicas-Universidad Autónoma de Madrid (CSIC-UAM), 28029 Madrid, Spain.ORCID 0000-0001-8983-6362
Luis Exequiel IbarraInstituto de Biotecnología Ambiental y Salud (INBIAS), Universidad Nacional de Río Cuarto (UNRC) y CONICET, Córdoba X5800BIA, Argentina.ORCID 0000-0002-6077-7992
María Serrano-TorresInstituto de Investigaciones Biomédicas "Alberto Sols", Consejo Superior de Investigaciones Científicas-Universidad Autónoma de Madrid (CSIC-UAM), 28029 Madrid, Spain.
Balbino YagüeInstituto de Investigaciones Biomédicas "Alberto Sols", Consejo Superior de Investigaciones Científicas-Universidad Autónoma de Madrid (CSIC-UAM), 28029 Madrid, Spain.
Matías Daniel CaverzánDepartamento de Biología Molecular, Facultad de Ciencias Exactas, Fisicoquímicas y Naturales, Universidad Nacional de Río Cuarto (UNRC), Córdoba X5800BIA, Argentina.ORCID 0000-0002-7362-2770
Carlos Alberto ChestaInstituto de Investigaciones en Tecnologías Energéticas y Materiales Avanzados (IITEMA), Universidad Nacional de Río Cuarto y CONICET, Córdoba X5800BIA, Argentina.
Rodrigo Emiliano PalaciosInstituto de Investigaciones en Tecnologías Energéticas y Materiales Avanzados (IITEMA), Universidad Nacional de Río Cuarto y CONICET, Córdoba X5800BIA, Argentina.
Pilar López-LarrubiaInstituto de Investigaciones Biomédicas "Alberto Sols", Consejo Superior de Investigaciones Científicas-Universidad Autónoma de Madrid (CSIC-UAM), 28029 Madrid, Spain.ORCID 0000-0002-5141-8736
Consejo Nacional de Investigaciones Científicas y Técnicas · ARConsejo Superior de Investigaciones Científicas · ES

Funding

Agencia Nacional de Promoción Científica y Tecnológica 2676/18, 3577/18Comunidad de Madrid S2017/BMD-3688Ministerio de Economía y Competitividad SAF2017-83043-RSecretaría de Ciencia y Técnica, Universidad Nacional de Río Cuarto PPI-SECyT UNRC
6 · The paper itself

Abstract

Conjugated polymer nanoparticles (CPNs) have emerged as advanced polymeric nanoplatforms in biomedical applications by virtue of extraordinary properties including high fluorescence brightness, large absorption coefficients of one and two-photons, and excellent photostability and colloidal stability in water and physiological medium. In addition, low cytotoxicity, easy functionalization, and the ability to modify CPN photochemical properties by the incorporation of dopants, convert them into excellent theranostic agents with multifunctionality for imaging and treatment. In this work, CPNs were designed and synthesized by incorporating a metal oxide magnetic core (Fe

Indexed as

conjugated polymerglioblastomairon oxide nanoparticlesMRInanoparticlespreclinical trialstheranostic

Identifiers

PMID34452219
PMCPMC8400017
OpenAlexW3194986889

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.