Evidence map›Paper›PMID 34452216›Full record

ArticlePharmaceutics2021

Simple and Fast DNA Based Sensor System for Screening of Small-Molecule Compounds Targeting Eukaryotic Topoisomerase 1.

Kamilla Vandsø Petersen, Asier Selas, Kirstine Mejlstrup Hymøller, Karol Mizielinski, Maria Thorsager, Magnus Stougaard, Concepcion Alonso, Francisco Palacios, Yolanda Pérez-Pertejo, Rosa M Reguera and 3 more

Open access · goldAbstract read
In one paragraph

Article in Pharmaceutics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.5field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 6 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 3 institutions in 2 countries.

Kamilla Vandsø PetersenDepartment of Molecular Biology and Genetics, Aarhus University, 8000 Aarhus, Denmark.
Asier SelasDepartment of Organic Chemistry, University of Basque Country (UPV/EHU), 01006 Vitoria-Gasteiz, Spain.ORCID 0000-0001-7327-668X
Kirstine Mejlstrup HymøllerDepartment of Molecular Biology and Genetics, Aarhus University, 8000 Aarhus, Denmark.
Karol MizielinskiVPCIR Biosciences ApS., 8000 Aarhus, Denmark.
Maria ThorsagerVPCIR Biosciences ApS., 8000 Aarhus, Denmark.
Magnus StougaardDepartment of Clinical Medicine, Aarhus University, 8000 Aarhus, Denmark.
Concepcion AlonsoDepartment of Organic Chemistry, University of Basque Country (UPV/EHU), 01006 Vitoria-Gasteiz, Spain.ORCID 0000-0003-0866-3493
Francisco PalaciosDepartment of Organic Chemistry, University of Basque Country (UPV/EHU), 01006 Vitoria-Gasteiz, Spain.ORCID 0000-0001-6365-0324
Yolanda Pérez-PertejoDepartment of Biomedical Sciences, University of Leon (ULE), 24071 Leon, Spain.
Rosa M RegueraDepartment of Biomedical Sciences, University of Leon (ULE), 24071 Leon, Spain.ORCID 0000-0001-9148-2997
Rafael Balaña-FouceDepartment of Biomedical Sciences, University of Leon (ULE), 24071 Leon, Spain.ORCID 0000-0003-0418-6116
Birgitta R KnudsenDepartment of Molecular Biology and Genetics, Aarhus University, 8000 Aarhus, Denmark.
Cinzia TesauroVPCIR Biosciences ApS., 8000 Aarhus, Denmark.ORCID 0000-0003-2986-9618
Aarhus University · DKUniversidad de León · ESUniversity of the Basque Country · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

colorimetric readoutdrug screeningenzyme activityREEADrolling circle amplificationsmall-molecule compoundstopoisomerase 1

Identifiers

PMID34452216
PMCPMC8401307
OpenAlexW3194878444

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.